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Ibrutinib and Rituximab Compared with Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients with Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Trial Status: Closed to Accrual

This randomized phase III trial studies ibrutinib and rituximab to see how well they work compared to fludarabine phosphate, cyclophosphamide, and rituximab in treating patients with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as fludarabine phosphate and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as rituximab, interfere with the ability of cancer cells to grow and spread. It is not yet known whether fludarabine phosphate, cyclophosphamide, and rituximab may work better than ibrutinib and rituximab in treating patients with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma.

Inclusion Criteria

  • Diagnosis of CLL according to the National Cancer Institute (NCI)/Internal Workshop on Chronic Lymphocytic Leukemia (IWCLL) criteria or small lymphocytic lymphoma (SLL) according to the World Health Organization (WHO) criteria; this includes previous documentation of: * Biopsy-proven small lymphocytic lymphoma or * Diagnosis of CLL according to the NCI/IWCLL criteria as evidenced by all of the following: ** Peripheral blood lymphocyte count of greater than 5 x 10^9/L ** Immunophenotype consistent with CLL defined as: *** The predominant population of lymphocytes share both B-cell antigens (cluster of differentiation [CD]19, CD20 [typically dim expression], or CD23) as well as CD5 in the absence of other pan-T-cell markers (CD3, CD2, etc) *** Clonality as evidenced by kappa or lambda light chain restriction (typically dim immunoglobulin expression) * Negative FISH analysis for t(11;14)(immunoglobulin heavy locus [IgH]/cyclin D1 [CCND1]) on peripheral blood or tissue biopsy (e.g. marrow aspirate) or negative immunohistochemical stains for cyclin D1 staining on involved tissue biopsy (e.g. marrow aspirate or lymph node biopsy)
  • No prior chemotherapy, Bruton's tyrosine kinase (BTK) inhibitor therapy, or monoclonal anti-body therapy for treatment of CLL or SLL
  • Has met at least one of the following indications for treatment: * Evidence of progressive marrow failure as manifested by the development of worsening anemia (hemoglobin [Hg] < 11 g/dl) and/or thrombocytopenia (platelets < 100 x 10^9/L) * Symptomatic or progressive lymphadenopathy, splenomegaly, or hepatomegaly * One or more of the following disease-related symptoms: ** Weight loss >= 10% within the previous 6 months ** Grade 2 or 3 fatigue attributed to CLL ** Fevers > 100.5 Fahrenheit (F) for 2 weeks without evidence of infection ** Clinically significant night sweats without evidence of infection * Progressive lymphocytosis (not due to the effects of corticosteroids) with an increase of > 50% over a two-month period or an anticipated doubling time of less than six months
  • ECOG performance status between 0-2
  • Life expectancy of >= 12 months
  • Ability to tolerate FCR based therapy
  • No deletion of 17p13 on cytogenetic analysis by FISH
  • Glomerular filtration rate (GFR) > 40 mL/minute as calculated by the Cockcroft-Gault formula
  • Total bilirubin =< 2.5 x upper limit of normal (ULN) unless due to Gilbert's disease; for those with a total bilirubin > 2.5 x ULN, a direct bilirubin should be performed and must be < 1.5 mg/dL for Gilbert's to be diagnosed; if value is higher due to hepatic involvement by CLL, patient is eligible
  • Serum glutamic oxaloacetic transaminase (SGOT) aspartate transaminase (AST)/serum glutamate-pyruvate transaminase (SGPT) alanine transaminase (ALT) =< 3.0 x the institutional ULN; if value is higher due to hepatic involvement by CLL, patient is eligible
  • Prothrombin time (PT)/international normalized ratio (INR) < 1.5 ULN and partial thromboplastin time (PTT) activated partial thromboplastin time (aPTT) < 1.5 X ULN; if value is higher due to hepatic involvement by CLL, patient is eligible
  • No active hemolytic anemia requiring immunosuppressive therapy or other pharmacologic treatment; patients who have a positive Coombs test but no evidence of hemolysis are NOT excluded from participation
  • No current use of corticosteroids; EXCEPTION: low doses of steroids (< 10 mg of prednisone or equivalent dose of other steroid) used for treatment of non-hematologic medical condition (e.g. chronic adrenal insufficiency) is permitted
  • No previous use of corticosteroids for autoimmune complications that have developed since the initial diagnosis of CLL; prior use of corticosteroids for reasons other than treatment of autoimmune complications is allowed
  • No other active primary malignancy (other than non-melanomatous skin cancer or carcinoma in situ of the cervix) requiring treatment or limiting expected survival to =< 2 years; NOTE: if there is a history of prior malignancy, they must not be receiving other specific treatment (other than hormonal therapy for their cancer)
  • Able to adhere to the study visit schedule and other protocol requirements
  • No major surgery within the last 4 weeks (28 days) of first dose of study drug or minor surgery within 3 days of first dose of study drug
  • No radiation therapy =< 4 weeks prior to registration
  • Patients with human immunodeficiency virus (HIV) infection may be eligible provided they meet the following criteria: * CD4-positive cell count >= lower limit of institutional normal * HIV viral load < 10,000 copies HIV ribonucleic acid (RNA)/mL (if not on anti-HIV therapy) OR < 50 copies HIV RNA/mL (if on anti-HIV therapy) * No evidence of hepatitis B or C infection * No evidence of resistant strains of HIV * No history of acquired immune deficiency syndrome (AIDS)-defining condition
  • Patients must not have any of the following conditions: * Congestive heart failure or New York Heart Association Functional Classification III or IV congestive heart failure * History of myocardial infarction, unstable angina, or acute coronary syndrome within 6 months prior to registration * Recent infections requiring systemic treatment; need to have completed anti-biotic therapy > 14 days before the first dose of study drug * Cerebral vascular accident or intracranial bleed within the last 6 months * Infection with known chronic, active hepatitis C * Serologic status reflecting active hepatitis B or C infection; patients that are positive for hepatitis B core antibody, hepatitis B surface antigen (HBsAg), or hepatitis C antibody must have a negative polymerase chain reaction (PCR) prior to enrollment (PCR positive patients will be excluded)
  • Patients are not eligible if they require treatment with a strong cytochrome P450 (CYP) family 3, subfamily A (3A) inhibitor
  • Patients may not be on any other investigational agents
  • Patients may not have received warfarin or another vitamin K antagonist in the preceding 30 days
  • Women must not be pregnant or breast-feeding; female patients of childbearing potential must have a negative serum pregnancy test within 2 weeks prior to registration to rule out pregnancy; female patients who are of non-reproductive potential are those who are post-menopausal by history (i.e. no menses for >= 1 year); OR history of hysterectomy; OR history of bilateral tubal ligation; OR history of bilateral oophorectomy
  • Women of childbearing potential and sexually active males must be strongly advised to use an accepted and effective method of contraception or to abstain from sexual intercourse for 90 days after the last dose of study drug
  • Patient must be able to swallow capsules and not have the following conditions: * Disease significantly affecting gastrointestinal function * Resection of the stomach or small bowel * Symptomatic inflammatory bowel disease * Ulcerative colitis * Partial or complete bowel obstruction
  • Patient must not be on any other systemic immunosuppressant therapy other than corticosteroids within 28 days of the first dose of study drug
  • Patient must not be vaccinated with live, attenuated vaccines within 4 weeks of first dose of study drug
  • Patient must not have any known bleeding disorders (e.g., von Willebrand’s disease) or hemophilia
  • Patient must not have currently active, clinically significant hepatic impairment (>= moderate hepatic impairment according to the NCI/Child Pugh)

Alabama

Birmingham
University of Alabama at Birmingham Cancer Center
Status: COMPLETED
Contact: Harry Paul Erba
Phone: 205-934-0309

Alaska

Anchorage
Alaska Breast Care and Surgery LLC
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Alaska Oncology and Hematology LLC
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Alaska Regional Hospital
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Alaska Women's Cancer Care
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Anchorage Associates in Radiation Medicine
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Anchorage Oncology Centre
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Anchorage Radiation Therapy Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Katmai Oncology Group
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Providence Alaska Medical Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Fairbanks
Fairbanks Memorial Hospital
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394

Arizona

Scottsdale
Mayo Clinic in Arizona
Status: COMPLETED
Contact: Tait D. Shanafelt
Phone: 507-538-7623

Arkansas

Hot Springs
CHI Saint Vincent Cancer Center Hot Springs
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Jonesboro
Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Status: COMPLETED
Contact: Carroll Dean Scroggin
Phone: 870-936-7000
Little Rock
University of Arkansas for Medical Sciences
Status: COMPLETED
Contact: Pooja Motwani
Phone: 501-686-8274

California

Anaheim
Kaiser Permanente-Anaheim
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Antioch
Kaiser Permanente-Deer Valley Medical Center
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Arroyo Grande
PCR Oncology
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Auburn
Sutter Auburn Faith Hospital
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Sutter Cancer Centers Radiation Oncology Services-Auburn
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Baldwin Park
Kaiser Permanente-Baldwin Park
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Bellflower
Kaiser Permanente-Bellflower
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Berkeley
Alta Bates Summit Medical Center-Herrick Campus
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Burbank
Providence Saint Joseph Medical Center / Disney Family Cancer Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Burlingame
Mills-Peninsula Medical Center
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Cameron Park
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Castro Valley
Eden Hospital Medical Center
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Chico
Adventist Health Cancer Care Center Chico
Status: COMPLETED
Contact: Sam Mazj
Phone: 530-876-7995
Email: haleew@ah.org
Concord
John Muir Medical Center-Concord Campus
Status: COMPLETED
Contact: Kasra Karamlou
Phone: 925-674-2580
Davis
Sutter Davis Hospital
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Fontana
Kaiser Permanente-Fontana
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Fremont
Kaiser Permanente-Fremont
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Fresno
Kaiser Permanente-Fresno
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Greenbrae
Marin Cancer Care Inc
Status: COMPLETED
Contact: Peter David Eisenberg
Phone: 415-925-5000
Marin General Hospital
Status: COMPLETED
Contact: Peter David Eisenberg
Phone: 415-925-5000
Harbor City
Kaiser Permanente - Harbor City
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Irvine
Kaiser Permanente-Irvine
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Los Angeles
Kaiser Permanente Los Angeles Medical Center
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Kaiser Permanente-Cadillac
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Modesto
Kaiser Permanente-Modesto
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Memorial Medical Center
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Mountain View
Palo Alto Medical Foundation-Camino Division
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Palo Alto Medical Foundation-Gynecologic Oncology
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Novato
Sutter Cancer Research Consortium
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Oakland
Kaiser Permanente-Oakland
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Orange
UC Irvine Health / Chao Family Comprehensive Cancer Center
Status: COMPLETED
Contact: Deepa Jeyakumar
Phone: 877-827-8839
Palo Alto
Palo Alto Medical Foundation Health Care
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Stanford Cancer Institute Palo Alto
Status: COMPLETED
Contact: Steven Edward Coutre
Phone: 650-498-7061
Panorama City
Kaiser Permanente - Panorama City
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Redwood City
Kaiser Permanente-Redwood City
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Richmond
Kaiser Permanente-Richmond
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Riverside
Kaiser Permanente-Riverside
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Roseville
Kaiser Permanente-Roseville
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Sutter Cancer Centers Radiation Oncology Services-Roseville
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Sutter Roseville Medical Center
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Sacramento
Kaiser Permanente - Sacramento
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Kaiser Permanente-South Sacramento
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Sutter Medical Center Sacramento
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
San Diego
Kaiser Permanente-San Diego Mission
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
Kaiser Permanente-San Diego Zion
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
San Francisco
California Pacific Medical Center-Pacific Campus
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Kaiser Permanente-San Francisco
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
San Jose
Kaiser Permanente-Santa Teresa-San Jose
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Stanford Cancer Center South Bay
Status: COMPLETED
Contact: Steven Edward Coutre
Phone: 650-498-7061
San Leandro
Kaiser Permanente San Leandro
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
San Luis Obispo
Pacific Central Coast Health Center-San Luis Obispo
Status: COMPLETED
Contact: Brian Anthony DiCarlo
San Marcos
Kaiser Permanente-San Marcos
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455
San Rafael
Kaiser Permanente-San Rafael
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Santa Clara
Kaiser Permanente Medical Center - Santa Clara
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Santa Cruz
Palo Alto Medical Foundation-Santa Cruz
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Santa Rosa
Kaiser Permanente-Santa Rosa
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Sutter Pacific Medical Foundation
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
South San Francisco
Kaiser Permanente-South San Francisco
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Stockton
Kaiser Permanente-Stockton
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Sunnyvale
Palo Alto Medical Foundation-Sunnyvale
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Vacaville
Kaiser Permanente Medical Center-Vacaville
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Vallejo
Kaiser Permanente-Vallejo
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Sutter Solano Medical Center / Cancer Center
Status: COMPLETED
Contact: Jorge Alejandro Garcia-Young
Phone: 415-209-2686
Walnut Creek
John Muir Medical Center-Walnut Creek
Status: COMPLETED
Contact: Kasra Karamlou
Phone: 925-674-2580
Kaiser Permanente-Walnut Creek
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455
Woodland Hills
Kaiser Permanente-Woodland Hills
Status: COMPLETED
Contact: Jonathan A. Polikoff
Phone: 626-564-3455

Colorado

Aurora
Rocky Mountain Cancer Centers-Aurora
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
The Medical Center of Aurora
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Boulder
Boulder Community Hospital
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Rocky Mountain Cancer Centers-Boulder
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Colorado Springs
Penrose-Saint Francis Healthcare
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Rocky Mountain Cancer Centers-Penrose
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Denver
Colorado Blood Cancer Institute
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Denver Health Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Kaiser Permanente-Franklin
Status: COMPLETED
Contact: Alexander Menter
Phone: 303-614-1300
National Jewish Health-Main Campus
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Porter Adventist Hospital
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Presbyterian - Saint Lukes Medical Center - Health One
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Rocky Mountain Cancer Centers-Midtown
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Rocky Mountain Cancer Centers-Rose
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Rose Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
SCL Health Saint Joseph Hospital
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Western States Cancer Research NCORP
Status: CLOSED_TO_ACCRUAL
Contact: Keren Sturtz
Phone: 303-777-2663
Durango
Mercy Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Southwest Oncology PC
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Englewood
Mountain Blue Cancer Care Center - Swedish
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Swedish Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Golden
Mountain Blue Cancer Care Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
National Jewish Health-Western Hematology Oncology
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Greeley
North Colorado Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Greenwood Village
Rocky Mountain Cancer Centers-Greenwood Village
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Lafayette
Kaiser Permanente-Rock Creek
Status: COMPLETED
Contact: Alexander Menter
Phone: 303-614-1300
Lakewood
Rocky Mountain Cancer Centers-Lakewood
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Saint Anthony Hospital
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Littleton
Littleton Adventist Hospital
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Rocky Mountain Cancer Centers-Littleton
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Lone Tree
Kaiser Permanente-Lone Tree
Status: COMPLETED
Contact: Alexander Menter
Phone: 303-614-1300
Rocky Mountain Cancer Centers-Sky Ridge
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Sky Ridge Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Longmont
Longmont United Hospital
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Rocky Mountain Cancer Centers-Longmont
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Loveland
McKee Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Parker
Parker Adventist Hospital
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Rocky Mountain Cancer Centers-Parker
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Pueblo
Rocky Mountain Cancer Centers - Pueblo
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Saint Mary Corwin Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Thornton
Rocky Mountain Cancer Centers-Thornton
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Wheat Ridge
SCL Health Lutheran Medical Center
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663

Connecticut

Derby
Smilow Cancer Hospital-Derby Care Center
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702
Fairfield
Smilow Cancer Hospital Care Center-Fairfield
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702
Hartford
Smilow Cancer Hospital Care Center at Saint Francis
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Middletown
Middlesex Hospital
Status: COMPLETED
Contact: Susanna Hong
Phone: 860-358-2058
New Haven
Smilow Cancer Center / Yale-New Haven Hospital
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702
Yale University
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702
North Haven
Yale-New Haven Hospital North Haven Medical Center
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702
Orange
Smilow Cancer Hospital-Orange Care Center
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702
Torrington
Smilow Cancer Hospital-Torrington Care Center
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702
Trumbull
Smilow Cancer Hospital Care Center-Trumbull
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702
Waterbury
Smilow Cancer Hospital-Waterbury Care Center
Status: COMPLETED
Contact: Gottfried von Keudell
Phone: 203-785-5702

Delaware

Lewes
Beebe Medical Center
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Newark
Christiana Care Health System-Christiana Hospital
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Christiana Gynecologic Oncology LLC
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Delaware Clinical and Laboratory Physicians PA
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Helen F Graham Cancer Center
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Medical Oncology Hematology Consultants PA
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Rehoboth Beach
Beebe Health Campus
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Seaford
TidalHealth Nanticoke / Allen Cancer Center
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Wilmington
Christiana Care Health System-Wilmington Hospital
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227

Florida

Jacksonville
Baptist MD Anderson Cancer Center
Status: COMPLETED
Contact: Robert Anthony Zaiden
Phone: 904-202-7051
Lakeland
Lakeland Regional Health Hollis Cancer Center
Status: COMPLETED
Contact: Sushma Simha Nakka
Phone: 863-904-1900
Orlando
UF Cancer Center at Orlando Health
Status: COMPLETED
Contact: Julio Jose Hajdenberg
Phone: 321-841-7246

Georgia

Albany
Phoebe Putney Memorial Hospital
Status: COMPLETED
Contact: Jose M. Tongol
Phone: 229-312-2251
Atlanta
Emory University Hospital / Winship Cancer Institute
Status: COMPLETED
Contact: Leonard Thompson Heffner
Phone: 404-778-1868
Columbus
John B Amos Cancer Center
Status: COMPLETED
Contact: Andrew W. Pippas
Phone: 706-660-6404
Macon
Central Georgia Gynecologic Oncology
Status: COMPLETED
Contact: Frederick M. Schnell
Phone: 478-633-1226
Medical Center of Central Georgia
Status: COMPLETED
Contact: Frederick M. Schnell
Phone: 478-633-1226
Savannah
Lewis Cancer and Research Pavilion at Saint Joseph's / Candler
Status: COMPLETED
Contact: Grant Carlton Lewis
Phone: 912-350-8568

Hawaii

Honolulu
Kaiser Permanente Moanalua Medical Center
Status: COMPLETED
Contact: Tatjana Kolevska
Phone: 626-564-3455

Idaho

Boise
Saint Alphonsus Cancer Care Center-Boise
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Saint Luke's Mountain States Tumor Institute
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Coeur D'Alene
Kootenai Medical Center
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Fruitland
Saint Luke's Cancer Institute - Fruitland
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Meridian
Saint Luke's Cancer Institute - Meridian
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Nampa
Saint Luke's Cancer Institute - Nampa
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Post Falls
Kootenai Cancer Center
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Sandpoint
Kootenai Cancer Clinic
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Twin Falls
Saint Luke's Cancer Institute - Twin Falls
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412

Illinois

Aurora
Rush - Copley Medical Center
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532
Bloomington
Illinois CancerCare-Bloomington
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Saint Joseph Medical Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Canton
Illinois CancerCare-Canton
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Carbondale
Memorial Hospital of Carbondale
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Carthage
Illinois CancerCare-Carthage
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Centralia
Centralia Oncology Clinic
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Chicago
Northwestern University
Status: COMPLETED
Contact: Shuo Ma
Phone: 312-695-1301
University of Chicago Comprehensive Cancer Center
Status: COMPLETED
Contact: Michael J. Thirman
Phone: 773-834-7424
Danville
Carle on Vermilion
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532
Decatur
Cancer Care Specialists of Illinois - Decatur
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Decatur Memorial Hospital
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Effingham
Carle Physician Group-Effingham
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532
Crossroads Cancer Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Elk Grove Village
AMITA Health Alexian Brothers Medical Center
Status: COMPLETED
Contact: Bruce B. Bank
Phone: 847-952-7164
Eureka
Illinois CancerCare-Eureka
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Evanston
NorthShore University HealthSystem-Evanston Hospital
Status: COMPLETED
Contact: David L. Grinblatt
Phone: 847-570-2109
Galesburg
Illinois CancerCare-Galesburg
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Western Illinois Cancer Treatment Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Geneva
Northwestern Medicine Cancer Center Delnor
Status: COMPLETED
Contact: Robert A. Bayer
Phone: 630-315-1918
Glenview
NorthShore University HealthSystem-Glenbrook Hospital
Status: COMPLETED
Contact: David L. Grinblatt
Phone: 847-570-2109
Highland Park
Hematology Oncology Associates of Illinois-Highland Park
Status: COMPLETED
Contact: Shuo Ma
Phone: 312-695-1301
NorthShore University HealthSystem-Highland Park Hospital
Status: COMPLETED
Contact: David L. Grinblatt
Phone: 847-570-2109
Joliet
Joliet Oncology-Hematology Associates Limited
Status: CLOSED_TO_ACCRUAL
Contact: Kulumani M. Sivarajan
Phone: 815-730-3098
Kankakee
Presence Saint Mary's Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Shuo Ma
Phone: 312-695-1301
Kewanee
Illinois CancerCare-Kewanee Clinic
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Libertyville
AMG Libertyville - Oncology
Status: COMPLETED
Contact: Shuo Ma
Phone: 312-695-1301
Macomb
Illinois CancerCare-Macomb
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Mattoon
Carle Physician Group-Mattoon / Charleston
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532
Maywood
Loyola University Medical Center
Status: COMPLETED
Contact: Kathleen Wren Phelan
Phone: 708-226-4357
Moline
Trinity Medical Center
Status: COMPLETED
Contact: David Martens Spector
Phone: 309-779-4200
Mount Vernon
Good Samaritan Regional Health Center
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
New Lenox
UC Comprehensive Cancer Center at Silver Cross
Status: COMPLETED
Contact: Michael J. Thirman
Phone: 773-834-7424
Niles
Illinois Cancer Specialists-Niles
Status: COMPLETED
Contact: Shuo Ma
Phone: 312-695-1301
Normal
Community Cancer Center Foundation
Status: COMPLETED
Contact: Nguyet Anh Le-Lindqwister
Phone: 800-793-2262
O'Fallon
Cancer Care Center of O'Fallon
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Oak Lawn
Advocate Christ Medical Center
Status: COMPLETED
Contact: Rami Yacoub Haddad
Phone: 800-323-8622
Ottawa
Illinois CancerCare-Ottawa Clinic
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Radiation Oncology of Northern Illinois
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Pekin
Illinois CancerCare-Pekin
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Peoria
Illinois CancerCare-Peoria
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Methodist Medical Center of Illinois
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
OSF Saint Francis Medical Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Peru
Illinois CancerCare-Peru
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Valley Radiation Oncology
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Princeton
Illinois CancerCare-Princeton
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Rockford
SwedishAmerican Regional Cancer Center / ACT
Status: COMPLETED
Contact: Harvey E. Einhorn
Phone: 779-696-9400
Skokie
Hematology Oncology Associates of Illinois - Skokie
Status: COMPLETED
Contact: Shuo Ma
Phone: 312-695-1301
North Shore Medical Center
Status: COMPLETED
Contact: David L. Grinblatt
Phone: 847-570-2109
Springfield
Central Illinois Hematology Oncology Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Memorial Medical Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Southern Illinois University School of Medicine
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Springfield Clinic
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Urbana
Carle Cancer Center
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532
The Carle Foundation Hospital
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532
Warrenville
Northwestern Medicine Cancer Center Warrenville
Status: COMPLETED
Contact: Robert A. Bayer
Phone: 630-315-1918
Yorkville
Rush-Copley Healthcare Center
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532

Indiana

Anderson
Saint Vincent Anderson Regional Hospital / Cancer Center
Status: COMPLETED
Contact: Ubaidullah Sharief
Phone: 765-646-8358
Michigan City
Franciscan Saint Anthony Health-Michigan City
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532
Woodland Cancer Care Center
Status: COMPLETED
Contact: Maria T. Grosse-Perdekamp
Phone: 800-446-5532
Mishawaka
Memorial Regional Cancer Center Day Road
Status: COMPLETED
Contact: Thomas Joseph Reid
Phone: 800-284-7370
Richmond
Reid Health
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
South Bend
Memorial Hospital of South Bend
Status: COMPLETED
Contact: Thomas Joseph Reid
Phone: 800-284-7370

Iowa

Ames
Mary Greeley Medical Center
Status: COMPLETED
Contact: Joseph James Merchant
Phone: 515-239-2621
McFarland Clinic PC - Ames
Status: COMPLETED
Contact: Joseph James Merchant
Phone: 515-239-2621
Boone
McFarland Clinic PC-Boone
Status: COMPLETED
Contact: Joseph James Merchant
Phone: 515-239-2621
Clive
Medical Oncology and Hematology Associates-West Des Moines
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Mercy Cancer Center-West Lakes
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Council Bluffs
Alegent Health Mercy Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Creston
Greater Regional Medical Center
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Des Moines
Medical Oncology and Hematology Associates-Laurel
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Mercy Medical Center - Des Moines
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Fort Dodge
McFarland Clinic PC-Trinity Cancer Center
Status: COMPLETED
Contact: Joseph James Merchant
Phone: 515-239-2621
Jefferson
McFarland Clinic PC-Jefferson
Status: COMPLETED
Contact: Joseph James Merchant
Phone: 515-239-2621
Marshalltown
McFarland Clinic PC-Marshalltown
Status: COMPLETED
Contact: Joseph James Merchant
Phone: 515-239-2621
Mason City
Mercy Medical Center - North Iowa
Status: COMPLETED
Contact: Arvind Y. Vemula
Phone: 800-433-3883
Sioux City
Mercy Medical Center-Sioux City
Status: COMPLETED
Contact: Donald B. Wender
Phone: 712-252-0088
Saint Luke's Regional Medical Center
Status: COMPLETED
Contact: Donald B. Wender
Phone: 712-252-0088
Siouxland Regional Cancer Center
Status: COMPLETED
Contact: Donald B. Wender
Phone: 712-252-0088
Spencer
Abben Cancer Center
Status: CLOSED_TO_ACCRUAL
Contact: Addison R. Tolentino
Phone: 816-932-2677
Waterloo
MercyOne Waterloo Medical Center
Status: COMPLETED
Contact: Mohammed T. Masri
Phone: 319-272-2070
West Des Moines
Mercy Medical Center-West Lakes
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119

Kansas

Chanute
Cancer Center of Kansas - Chanute
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Dodge City
Cancer Center of Kansas - Dodge City
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
El Dorado
Cancer Center of Kansas - El Dorado
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Fort Scott
Cancer Center of Kansas - Fort Scott
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Independence
Cancer Center of Kansas-Independence
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Kingman
Cancer Center of Kansas-Kingman
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Lawrence
Lawrence Memorial Hospital
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Lenexa
Kansas Institute of Medicine Cancer and Blood Center
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Minimally Invasive Surgery Hospital
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Liberal
Cancer Center of Kansas-Liberal
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Newton
Cancer Center of Kansas - Newton
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Overland Park
Menorah Medical Center
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Saint Luke's South Hospital
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Parsons
Cancer Center of Kansas - Parsons
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Prairie Village
Kansas City NCI Community Oncology Research Program
Status: CLOSED_TO_ACCRUAL
Contact: Rakesh Gaur
Phone: 816-932-2677
Pratt
Cancer Center of Kansas - Pratt
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Salina
Cancer Center of Kansas - Salina
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Topeka
Cotton O'Neil Cancer Center / Stormont Vail Health
Status: COMPLETED
Contact: Mehmood Hussain Hashmi
Phone: 785-270-4963
Wellington
Cancer Center of Kansas - Wellington
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Wichita
Ascension Via Christi Hospitals Wichita
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Associates In Womens Health
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Cancer Center of Kansas - Wichita
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Cancer Center of Kansas-Wichita Medical Arts Tower
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467
Winfield
Cancer Center of Kansas - Winfield
Status: COMPLETED
Contact: Shaker R. Dakhil
Phone: 316-262-4467

Kentucky

Bardstown
Flaget Memorial Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Corbin
Commonwealth Cancer Center-Corbin
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Crestview Hills
Oncology Hematology Care Inc-Crestview
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Lexington
Saint Joseph Hospital East
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Saint Joseph Radiation Oncology Resource Center
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Louisville
Jewish Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Jewish Hospital Medical Center Northeast
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Saints Mary and Elizabeth Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Shepherdsville
Jewish Hospital Medical Center South
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119

Louisiana

Baton Rouge
Ochsner Health Center-Summa
Status: COMPLETED
Contact: Robert Van Buren Emmons
Phone: 888-562-4763
Kenner
Ochsner Medical Center Kenner
Status: COMPLETED
Contact: Robert Van Buren Emmons
Phone: 888-562-4763
Monroe
Ochsner LSU Health Monroe Medical Center
Status: COMPLETED
Contact: Richard P. Mansour
Phone: 318-813-1412
New Orleans
Ochsner Medical Center Jefferson
Status: COMPLETED
Contact: Robert Van Buren Emmons
Phone: 888-562-4763
Shreveport
CHRISTUS Highland Medical Center
Status: COMPLETED
Contact: Robert Van Buren Emmons
Phone: 888-562-4763
LSU Health Sciences Center at Shreveport
Status: COMPLETED
Contact: Richard P. Mansour
Phone: 318-813-1412

Maine

Augusta
Harold Alfond Center for Cancer Care
Status: COMPLETED
Contact: Thomas H. Openshaw
Phone: 800-987-3005
Bangor
Eastern Maine Medical Center
Status: COMPLETED
Contact: Thomas H. Openshaw
Phone: 800-987-3005
Brewer
Lafayette Family Cancer Center-EMMC
Status: COMPLETED
Contact: Thomas H. Openshaw
Phone: 800-987-3005
Rockport
Penobscot Bay Medical Center
Status: COMPLETED
Contact: Thomas H. Openshaw
Phone: 800-987-3005

Maryland

Baltimore
Saint Agnes Hospital
Status: COMPLETED
Contact: Carole Brennan Miller
Phone: 410-368-2910
University of Maryland / Greenebaum Cancer Center
Status: COMPLETED
Contact: Seung Tae Lee
Phone: 800-888-8823

Massachusetts

Beverly
Beverly Hospital
Status: COMPLETED
Contact: Angus P. McIntyre
Phone: 978-283-4000extn559
Boston
Eastern Cooperative Oncology Group
Status: CLOSED_TO_ACCRUAL
Contact: Tait D. Shanafelt
Phone: 507-284-2358
Tufts Medical Center
Status: COMPLETED
Contact: Andreas Kirschmer Klein
Phone: 617-636-5000
Burlington
Lahey Hospital and Medical Center
Status: COMPLETED
Contact: Tarun Kewalramani
Phone: 781-744-8027
Gloucester
Addison Gilbert Hospital
Status: COMPLETED
Contact: Angus P. McIntyre
Phone: 978-283-4000extn559
Springfield
Baystate Medical Center
Status: COMPLETED
Contact: Syed S. Ali
Phone: 413-794-3565
Winchester
Winchester Hospital
Status: COMPLETED
Contact: Tarun Kewalramani
Phone: 781-744-8027
Worcester
UMass Memorial Medical Center - University Campus
Status: COMPLETED
Contact: Muthalagu Ramanathan
Phone: 508-856-3216

Michigan

Adrian
Bixby Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Hickman Cancer Center
Status: COMPLETED
Contact: Rex B. Mowat
Phone: 800-444-3561
Ann Arbor
Michigan Cancer Research Consortium NCORP
Status: ADMINISTRATIVELY_COMPLETE
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Saint Joseph Mercy Hospital
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Brownstown
Henry Ford Cancer Institute-Downriver
Status: COMPLETED
Contact: Robert Anthony Chapman
Phone: 313-916-1784
Clinton Township
Henry Ford Macomb Hospital-Clinton Township
Status: COMPLETED
Contact: Robert Anthony Chapman
Phone: 313-916-1784
Dearborn
Beaumont Hospital - Dearborn
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Henry Ford Medical Center-Fairlane
Status: COMPLETED
Contact: Robert Anthony Chapman
Phone: 313-916-1784
Detroit
Ascension Saint John Hospital
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Henry Ford Hospital
Status: COMPLETED
Contact: Robert Anthony Chapman
Phone: 313-916-1784
Wayne State University / Karmanos Cancer Institute
Status: COMPLETED
Contact: Jay Yang
Phone: 313-576-9363
Escanaba
Green Bay Oncology - Escanaba
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Farmington Hills
Beaumont Hospital - Farmington Hills
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Weisberg Cancer Treatment Center
Status: COMPLETED
Contact: Jay Yang
Phone: 313-576-9363
Flint
Genesys Hurley Cancer Institute
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Hurley Medical Center
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Grosse Pointe
William Beaumont Hospital-Grosse Pointe
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Iron Mountain
Green Bay Oncology - Iron Mountain
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Jackson
Allegiance Health
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Kalamazoo
West Michigan Cancer Center
Status: COMPLETED
Contact: Sunil Nagpal
Phone: 269-373-7458
Lansing
Sparrow Hospital
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Livonia
Saint Mary Mercy Hospital
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Monroe
Mercy Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Monroe Cancer Center
Status: COMPLETED
Contact: Jeffrey H Muler
Phone: 419-824-1842
Toledo Clinic Cancer Centers-Monroe
Status: COMPLETED
Contact: Rex B. Mowat
Phone: 800-444-3561
Novi
Ascension Providence Hospitals - Novi
Status: COMPLETED
Contact: Robert Eric Bloom
Phone: 248-849-5337
Henry Ford Medical Center-Columbus
Status: COMPLETED
Contact: Robert Anthony Chapman
Phone: 313-916-1784
Pontiac
Saint Joseph Mercy Oakland
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Port Huron
Lake Huron Medical Center
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 702-384-0013
Roseville
Michigan Cancer Specialists
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Royal Oak
Cancer Care Associates PC
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Comprehensive Medical Center PLLC
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Hematology and Oncology Consultants PC
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Oakland Colon Rectal Associates
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Oakland Medical Group
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
William Beaumont Hospital-Royal Oak
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Saginaw
Ascension Saint Mary's Hospital
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
Southfield
Ascension Providence Hospitals - Southfield
Status: COMPLETED
Contact: Robert Eric Bloom
Phone: 248-849-5337
Sterling Heights
Mitchell Folbe MD PC
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Premier Hematology Oncology Care
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Troy
Claudia BR Herke MD PC
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Hematology Oncology Consultants PC-Troy
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Michigan Institute of Urology-Town Center
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
William Beaumont Hospital - Troy
Status: COMPLETED
Contact: Ishmael A. Jaiyesimi
Phone: 248-551-7695
Warren
Saint John Macomb-Oakland Hospital
Status: COMPLETED
Contact: Christopher M. Reynolds
Phone: 734-712-4673
West Bloomfield
Henry Ford West Bloomfield Hospital
Status: COMPLETED
Contact: Robert Anthony Chapman
Phone: 313-916-1784

Minnesota

Bemidji
Sanford Joe Lueken Cancer Center
Status: COMPLETED
Contact: Preston D. Steen
Phone: 701-234-6161
Brainerd
Essentia Health Saint Joseph's Medical Center
Status: COMPLETED
Contact: Bret E.B. Friday
Phone: 888-203-7267
Burnsville
Fairview Ridges Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Coon Rapids
Mercy Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Duluth
Essentia Health Cancer Center
Status: COMPLETED
Contact: Bret E.B. Friday
Phone: 888-203-7267
Essentia Health Saint Mary's Medical Center
Status: COMPLETED
Contact: Bret E.B. Friday
Phone: 888-203-7267
Miller-Dwan Hospital
Status: COMPLETED
Contact: Bret E.B. Friday
Phone: 888-203-7267
Edina
Fairview Southdale Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Fergus Falls
Lake Region Healthcare Corporation-Cancer Care
Status: COMPLETED
Contact: Bret E.B. Friday
Phone: 888-203-7267
Fridley
Unity Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Hutchinson
Hutchinson Area Health Care
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Maplewood
Minnesota Oncology Hematology PA-Maplewood
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Saint John's Hospital - Healtheast
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Minneapolis
Abbott-Northwestern Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Health Partners Inc
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Hennepin County Medical Center
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
New Ulm
New Ulm Medical Center
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Robbinsdale
North Memorial Medical Health Center
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Rochester
Mayo Clinic in Rochester
Status: COMPLETED
Contact: Tait D. Shanafelt
Phone: 507-538-7623
Saint Louis Park
Metro Minnesota Community Oncology Research Consortium
Status: ADMINISTRATIVELY_COMPLETE
Contact: Joseph W. Leach
Phone: 952-993-1517
Park Nicollet Clinic - Saint Louis Park
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Saint Paul
Regions Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
United Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Shakopee
Saint Francis Regional Medical Center
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Stillwater
Lakeview Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Waconia
Ridgeview Medical Center
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Willmar
Rice Memorial Hospital
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Woodbury
Minnesota Oncology Hematology PA-Woodbury
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517

Missouri

Bolivar
Central Care Cancer Center - Bolivar
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Bonne Terre
Parkland Health Center-Bonne Terre
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Branson
Cox Cancer Center Branson
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Cape Girardeau
Saint Francis Medical Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Southeast Cancer Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Creve Coeur
Siteman Cancer Center at West County Hospital
Status: COMPLETED
Contact: Nancy L. Bartlett
Phone: 800-600-3606
Independence
Centerpoint Medical Center LLC
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Jefferson City
Capital Region Southwest Campus
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Joplin
Freeman Health System
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Mercy Hospital Joplin
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Kansas City
Heartland Hematology and Oncology Associates Incorporated
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Research Medical Center
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Saint Luke's Hospital of Kansas City
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Lee's Summit
Saint Luke's East - Lee's Summit
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Liberty
Liberty Radiation Oncology Center
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Rolla
Delbert Day Cancer Institute at PCRMC
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Mercy Clinic-Rolla-Cancer and Hematology
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Saint Joseph
Heartland Regional Medical Center
Status: COMPLETED
Contact: Rakesh Gaur
Phone: 816-932-2677
Saint Louis
Mercy Hospital Saint Louis
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Missouri Baptist Medical Center
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Saint Louis Cancer and Breast Institute-South City
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Siteman Cancer Center-South County
Status: COMPLETED
Contact: Nancy L. Bartlett
Phone: 800-600-3606
Washington University School of Medicine
Status: COMPLETED
Contact: Nancy L. Bartlett
Phone: 800-600-3606
Saint Peters
Siteman Cancer Center at Saint Peters Hospital
Status: COMPLETED
Contact: Nancy L. Bartlett
Phone: 800-600-3606
Sainte Genevieve
Sainte Genevieve County Memorial Hospital
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Springfield
CoxHealth South Hospital
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Mercy Hospital Springfield
Status: COMPLETED
Contact: Jay W. Carlson
Phone: 800-821-7532
Sullivan
Missouri Baptist Sullivan Hospital
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740
Sunset Hills
Missouri Baptist Outpatient Center-Sunset Hills
Status: COMPLETED
Contact: James Lloyd Wade
Phone: 217-876-4740

Montana

Anaconda
Community Hospital of Anaconda
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Billings
Billings Clinic Cancer Center
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Montana Cancer Consortium NCORP
Status: CLOSED_TO_ACCRUAL
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Saint Vincent Healthcare
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Bozeman
Bozeman Deaconess Hospital
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Butte
Saint James Community Hospital and Cancer Treatment Center
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Great Falls
Benefis Healthcare- Sletten Cancer Institute
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Great Falls Clinic
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Helena
Saint Peter's Community Hospital
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Kalispell
Kalispell Regional Medical Center
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Missoula
Community Medical Hospital
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Saint Patrick Hospital - Community Hospital
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274

Nebraska

Grand Island
CHI Health Saint Francis
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Kearney
CHI Health Good Samaritan
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Heartland Hematology and Oncology
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Lincoln
Nebraska Cancer Research Center
Status: COMPLETED
Contact: Gamini S. Soori
Phone: 402-393-3110
Nebraska Hematology and Oncology
Status: COMPLETED
Contact: Gamini S. Soori
Phone: 402-393-3110
Saint Elizabeth Regional Medical Center
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Southeast Nebraska Cancer Center - 68th Street Place
Status: COMPLETED
Contact: Gamini S. Soori
Phone: 402-393-3110
Norfolk
Faith Regional Health Services Carson Cancer Center
Status: COMPLETED
Contact: Gamini S. Soori
Phone: 402-393-3110
North Platte
Great Plains Health Callahan Cancer Center
Status: COMPLETED
Contact: Gamini S. Soori
Phone: 402-393-3110
Omaha
Alegent Health Bergan Mercy Medical Center
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Alegent Health Immanuel Medical Center
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Alegent Health Lakeside Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Creighton University Medical Center
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Hematology and Oncology Consultants PC
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Missouri Valley Cancer Consortium
Status: CLOSED_TO_ACCRUAL
Contact: Gamini S. Soori
Phone: 402-991-8070ext202
Nebraska Cancer Specialists - Omaha
Status: COMPLETED
Contact: Gamini S. Soori
Phone: 402-393-3110
Oncology Hematology West PC
Status: COMPLETED
Contact: Gamini S. Soori
Phone: 402-393-3110
University of Nebraska Medical Center
Status: COMPLETED
Contact: Robert Gregory Bociek
Phone: 402-559-6941
Papillion
Midlands Community Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Scottsbluff
Regional West Medical Center Cancer Center
Status: COMPLETED
Contact: Gamini S. Soori
Phone: 402-393-3110

Nevada

Henderson
21st Century Oncology-Henderson
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Cancer and Blood Specialists-Henderson
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada - Henderson
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Las Vegas Cancer Center-Henderson
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Las Vegas
21st Century Oncology
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
21st Century Oncology-Fort Apache
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
21st Century Oncology-Vegas Tenaya
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Cancer Therapy and Integrative Medicine
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Cancer and Blood Specialists-Shadow
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Cancer and Blood Specialists-Tenaya
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada - Central Valley
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada - Northwest
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada-Summerlin
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
HealthCare Partners Medical Group Oncology / Hematology-Centennial Hills
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
HealthCare Partners Medical Group Oncology / Hematology-Maryland Parkway
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
HealthCare Partners Medical Group Oncology / Hematology-San Martin
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
HealthCare Partners Medical Group Oncology / Hematology-Tenaya
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Las Vegas Cancer Center-Medical Center
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Nevada Cancer Research Foundation CCOP
Status: CLOSED_TO_ACCRUAL
Contact: John Allan Ellerton
Phone: 702-384-0013
OptumCare Cancer Care at Fort Apache
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Radiation Oncology Centers of Nevada Central
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Radiation Oncology Centers of Nevada Southeast
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Summerlin Hospital Medical Center
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013
Reno
Saint Mary's Regional Medical Center
Status: COMPLETED
Contact: John Allan Ellerton
Phone: 702-384-0013

New Hampshire

Dover
Wentworth-Douglass Hospital
Status: COMPLETED
Contact: Henry Leo Sonneborn
Phone: 603-740-2150

New Jersey

East Orange
Veterans Adminstration New Jersey Health Care System
Status: COMPLETED
Contact: Victor Tsu-Shih Chang
Phone: 800-475-2336
Newark
Newark Beth Israel Medical Center
Status: COMPLETED
Contact: Lori Schleicher
Phone: 973-926-7230

New Mexico

Albuquerque
University of New Mexico Cancer Center
Status: COMPLETED
Contact: Cecilia Ysabel Arana Yi
Phone: 505-272-6972

New York

Albany
New York Oncology Hematology PC - Albany Medical Center
Status: COMPLETED
Contact: Charles H. Weissman
Phone: 518-489-3612
Auburn
Hematology Oncology Associates of Central New York-Auburn
Status: CLOSED_TO_ACCRUAL
Contact: Jeffrey J. Kirshner
Phone: 315-472-7504
Buffalo
Roswell Park Cancer Institute
Status: COMPLETED
Contact: Seema Ali Bhat
Phone: 877-275-7724
Glens Falls
Glens Falls Hospital
Status: COMPLETED
Contact: George Fuad Atweh
Phone: 802-656-8990
Lake Success
Northwell Health / Center for Advanced Medicine
Status: COMPLETED
Contact: Jacqueline C. Barrientos
Phone: 516-734-8954
Liverpool
Hematology Oncology Associates of Central New York-Liverpool
Status: CLOSED_TO_ACCRUAL
Contact: Jeffrey J. Kirshner
Phone: 315-472-7504
Manhasset
North Shore University Hospital
Status: COMPLETED
Contact: Jacqueline C. Barrientos
Phone: 516-734-8954
Middletown
Garnet Health Medical Center
Status: COMPLETED
Contact: Jeffrey M. Stewart
Phone: 845-342-7609
New Hyde Park
Long Island Jewish Medical Center
Status: COMPLETED
Contact: Jacqueline C. Barrientos
Phone: 516-734-8954
Rochester
University of Rochester
Status: COMPLETED
Contact: Jonathan Willmann Friedberg
Phone: 585-275-5830
Rome
Hematology Oncology Associates of Central New York-Rome
Status: CLOSED_TO_ACCRUAL
Contact: Jeffrey J. Kirshner
Phone: 315-472-7504
Syracuse
Hematology Oncology Associates of Central New York-Onondaga Hill
Status: CLOSED_TO_ACCRUAL
Contact: Jeffrey J. Kirshner
Phone: 315-472-7504
State University of New York Upstate Medical University
Status: COMPLETED
Contact: Teresa Caroline Gentile
Phone: 315-464-5476

North Carolina

Asheville
AdventHealth Infusion Center Asheville
Status: COMPLETED
Contact: Raymond Thertulien
Phone: 855-774-5433
Messino Cancer Centers
Status: COMPLETED
Contact: Christopher H. Chay
Phone: 800-506-2550
Mission Hospital
Status: COMPLETED
Contact: Christopher H. Chay
Phone: 800-506-2550
Clinton
Sampson Radiation Oncology
Status: COMPLETED
Contact: James N. Atkins
Phone: 919-580-0000
Southeastern Medical Oncology Center-Clinton
Status: COMPLETED
Contact: James N. Atkins
Phone: 919-580-0000
Goldsboro
Southeastern Medical Oncology Center-Goldsboro
Status: COMPLETED
Contact: James N. Atkins
Phone: 919-580-0000
Wayne Memorial Hospital
Status: COMPLETED
Contact: James N. Atkins
Phone: 919-580-0000
Wayne Radiation Oncology
Status: COMPLETED
Contact: James N. Atkins
Phone: 919-580-0000
Hendersonville
AdventHealth Hendersonville
Status: COMPLETED
Contact: Raymond Thertulien
Phone: 855-774-5433
Hendersonville Hematology and Oncology at Pardee
Status: COMPLETED
Contact: James Earl Radford
Phone: 828-696-4716
Margaret R Pardee Memorial Hospital
Status: COMPLETED
Contact: James Earl Radford
Phone: 828-696-4716
Jacksonville
Onslow Memorial Hospital
Status: COMPLETED
Contact: James N. Atkins
Phone: 919-580-0000
Southeastern Medical Oncology Center-Jacksonville
Status: COMPLETED
Contact: James N. Atkins
Phone: 919-580-0000
Kinston
Vidant Oncology-Kinston
Status: COMPLETED
Contact: Peter Robins Watson
Phone: 252-559-2200
Winston-Salem
Wake Forest University Health Sciences
Status: COMPLETED
Contact: Leslie Renee Ellis
Phone: 336-713-6771

North Dakota

Bismarck
Sanford Bismarck Medical Center
Status: COMPLETED
Contact: Preston D. Steen
Phone: 701-234-6161
Fargo
Essentia Health Cancer Center-South University Clinic
Status: COMPLETED
Contact: Bret E.B. Friday
Phone: 888-203-7267
Sanford Broadway Medical Center
Status: COMPLETED
Contact: Preston D. Steen
Phone: 701-234-6161
Sanford Clinic North-Fargo
Status: COMPLETED
Contact: Preston D. Steen
Phone: 701-234-6161
Sanford Roger Maris Cancer Center
Status: COMPLETED
Contact: Preston D. Steen
Phone: 701-234-6161

Ohio

Akron
Cleveland Clinic Akron General
Status: COMPLETED
Contact: Esther Hoogland Rehmus
Phone: 330-344-6348
Beachwood
UHHS-Chagrin Highlands Medical Center
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Belpre
Strecker Cancer Center-Belpre
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Bowling Green
Toledo Clinic Cancer Centers-Bowling Green
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Centerville
Dayton Physicians LLC-Miami Valley South
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Miami Valley Hospital South
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Chardon
Geauga Hospital
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Chillicothe
Adena Regional Medical Center
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Cincinnati
Bethesda North Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Good Samaritan Hospital - Cincinnati
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Oncology Hematology Care Inc-Anderson
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Oncology Hematology Care Inc-Blue Ash
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Oncology Hematology Care Inc-Eden Park
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Oncology Hematology Care Inc-Kenwood
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Oncology Hematology Care Inc-Mercy West
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
TriHealth Cancer Institute-Anderson
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
TriHealth Cancer Institute-Westside
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
University of Cincinnati / Barrett Cancer Center
Status: COMPLETED
Contact: Tahir Latif
Phone: 513-558-4553
Cleveland
Case Western Reserve University
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
MetroHealth Medical Center
Status: COMPLETED
Contact: Bruce J. Averbook
Phone: 216-778-8526
Columbus
Columbus NCI Community Oncology Research Program
Status: ADMINISTRATIVELY_COMPLETE
Contact: John Philip Kuebler
Phone: 614-566-3275
Columbus Oncology and Hematology Associates Inc
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Doctors Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Grant Medical Center
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Mount Carmel East Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Mount Carmel Health Center West
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Riverside Methodist Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
The Mark H Zangmeister Center
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Dayton
Dayton NCI Community Oncology Research Program
Status: ADMINISTRATIVELY_COMPLETE
Contact: Howard M. Gross
Phone: 937-775-1350
Dayton Physician LLC-Miami Valley Hospital North
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Dayton Veterans Affairs Medical Center
Status: COMPLETED
Contact: Leonard Joseph Horwitz
Phone: 937-268-6511
Good Samaritan Hospital - Dayton
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Miami Valley Hospital
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Miami Valley Hospital North
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Delaware
Delaware Health Center-Grady Cancer Center
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Delaware Radiation Oncology
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Grady Memorial Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Elyria
Mercy Cancer Center-Elyria
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Fairfield
Oncology Hematology Care Inc-Healthplex
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Findlay
Armes Family Cancer Center
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Blanchard Valley Hospital
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Orion Cancer Care
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Franklin
Atrium Medical Center-Middletown Regional Hospital
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Dayton Physicians LLC-Atrium
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Greenville
Dayton Physicians LLC-Wayne
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Wayne Hospital
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Kettering
Greater Dayton Cancer Center
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Kettering Medical Center
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Lancaster
Fairfield Medical Center
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Lancaster Radiation Oncology
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Lima
Lima Memorial Hospital
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Mansfield
OhioHealth Mansfield Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Marietta
Marietta Memorial Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Marion
OhioHealth Marion General Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Maumee
Toledo Clinic Cancer Centers-Maumee
Status: COMPLETED
Contact: Rex B. Mowat
Phone: 800-444-3561
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Status: COMPLETED
Contact: Rex B. Mowat
Phone: 800-444-3561
Mayfield Heights
UH Seidman Cancer Center at Landerbrook Health Center
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Mentor
UH Seidman Cancer Center at Lake Health Mentor Campus
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Middleburg Heights
UH Seidman Cancer Center at Southwest General Hospital
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Middletown
Dayton Physicians LLC-Signal Point
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Mount Vernon
Knox Community Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Newark
Licking Memorial Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Newark Radiation Oncology
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Oregon
Saint Charles Hospital
Status: COMPLETED
Contact: Rex B. Mowat
Phone: 800-444-3561
Toledo Clinic Cancer Centers-Oregon
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Parma
University Hospitals Parma Medical Center
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Portsmouth
Southern Ohio Medical Center
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Sidney
Dayton Physicians LLC-Wilson
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Springfield
Springfield Regional Cancer Center
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Springfield Regional Medical Center
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Sylvania
ProMedica Flower Hospital
Status: COMPLETED
Contact: Jeffrey H Muler
Phone: 419-824-1842
Tiffin
Mercy Hospital of Tiffin
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Toledo
Mercy Saint Anne Hospital
Status: COMPLETED
Contact: Rex B. Mowat
Phone: 800-444-3561
Saint Vincent Mercy Medical Center
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Toledo Clinic Cancer Centers-Toledo
Status: COMPLETED
Contact: Rex B. Mowat
Phone: 800-444-3561
Toledo Community Hospital Oncology Program CCOP
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
University of Toledo
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Troy
Dayton Physicians LLC-Upper Valley
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Upper Valley Medical Center
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
WPAFB
Wright-Patterson Medical Center
Status: COMPLETED
Contact: Howard M. Gross
Phone: 937-775-1350
Wadsworth
University Hospitals Sharon Health Center
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Wauseon
Fulton County Health Center
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
West Chester
University Pointe
Status: COMPLETED
Contact: Tahir Latif
Phone: 513-558-4553
Westerville
Saint Ann's Hospital
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745
Westlake
UH Seidman Cancer Center at Saint John Medical Center
Status: COMPLETED
Contact: Hillard Michael Lazarus
Phone: 800-641-2422
Zanesville
Genesis Healthcare System Cancer Care Center
Status: COMPLETED
Contact: John Philip Kuebler
Phone: 614-488-2745

Oklahoma

Lawton
Cancer Centers of Southwest Oklahoma Research
Status: COMPLETED
Contact: Mohamad A Cherry
Phone: 405-271-8777
Oklahoma City
University of Oklahoma Health Sciences Center
Status: COMPLETED
Contact: Mohamad A Cherry
Phone: 405-271-8777

Oregon

Bend
Saint Charles Health System
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Clackamas
Clackamas Radiation Oncology Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Providence Cancer Institute Clackamas Clinic
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Coos Bay
Bay Area Hospital
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Milwaukie
Providence Milwaukie Hospital
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Newberg
Providence Newberg Medical Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Oregon City
Providence Willamette Falls Medical Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Portland
Kaiser Permanente Northwest
Status: COMPLETED
Contact: Nagendra Ranganatha Tirumali
Phone: 503-335-2400
Providence Portland Medical Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Providence Saint Vincent Medical Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412

Pennsylvania

Allentown
Lehigh Valley Hospital-Cedar Crest
Status: COMPLETED
Contact: Eliot L. Friedman
Phone: 610-402-2273
Beaver
UPMC-Heritage Valley Health System Beaver
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
Bethlehem
Lehigh Valley Hospital - Muhlenberg
Status: COMPLETED
Contact: Eliot L. Friedman
Phone: 610-402-2273
Bryn Mawr
Bryn Mawr Hospital
Status: COMPLETED
Contact: Albert S. DeNittis
Phone: 484-476-2649
Chadds Ford
Christiana Care Health System-Concord Health Center
Status: COMPLETED
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Danville
Geisinger Medical Center
Status: COMPLETED
Contact: Joseph Joe Lukose Vadakara
Phone: 570-271-5251
Erie
UPMC Hillman Cancer Center Erie
Status: COMPLETED
Contact: Philip H. Symes
Phone: 814-838-0448
Greensburg
UPMC Cancer Centers - Arnold Palmer Pavilion
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
Hazleton
Geisinger Medical Center-Cancer Center Hazleton
Status: COMPLETED
Contact: Joseph Joe Lukose Vadakara
Phone: 570-271-5251
Hershey
Penn State Milton S Hershey Medical Center
Status: COMPLETED
Contact: Jeffrey J. Pu
Phone: 717-531-3779
Johnstown
UPMC-Johnstown / John P. Murtha Regional Cancer Center
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
Lancaster
Lancaster General Hospital
Status: COMPLETED
Contact: Shyam S. Balepur
Phone: 717-544-0511
Lewisburg
Geisinger Medical Oncology-Lewisburg
Status: COMPLETED
Contact: Joseph Joe Lukose Vadakara
Phone: 570-271-5251
Lewistown
Lewistown Hospital
Status: COMPLETED
Contact: Joseph Joe Lukose Vadakara
Phone: 570-271-5251
McKeesport
UPMC Cancer Center at UPMC McKeesport
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
Media
Riddle Memorial Hospital
Status: COMPLETED
Contact: Albert S. DeNittis
Phone: 484-476-2649
Moon Township
UPMC-Coraopolis / Heritage Valley Radiation Oncology
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
Paoli
Paoli Memorial Hospital
Status: COMPLETED
Contact: Albert S. DeNittis
Phone: 484-476-2649
Philadelphia
Drexel University School of Medicine
Status: COMPLETED
Contact: Maneesh Jain
Phone: 215-762-3950
Thomas Jefferson University Hospital
Status: COMPLETED
Contact: Amy R. Mackenzie
Phone: 215-955-6084
University of Pennsylvania / Abramson Cancer Center
Status: COMPLETED
Contact: Anthony R. Mato
Phone: 800-474-9892
Pittsburgh
UPMC Jefferson Regional Radiation Oncology
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
UPMC-Magee Womens Hospital
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
UPMC-Passavant Hospital
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
UPMC-Presbyterian Hospital
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
UPMC-Saint Clair Hospital Cancer Center
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
UPMC-Saint Margaret
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
UPMC-Shadyside Hospital
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
University of Pittsburgh Cancer Institute (UPCI)
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
Pottstown
Pottstown Hospital
Status: COMPLETED
Contact: Wei Song
Phone: 610-327-7544
Pottsville
Geisinger Cancer Services-Pottsville
Status: COMPLETED
Contact: Joseph Joe Lukose Vadakara
Phone: 570-271-5251
Scranton
Hematology and Oncology Associates of North East Pennsylvania
Status: COMPLETED
Contact: Amy R. Mackenzie
Phone: 215-955-6084
Seneca
UPMC Cancer Center at UPMC Northwest
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
State College
Geisinger Medical Group
Status: COMPLETED
Contact: Joseph Joe Lukose Vadakara
Phone: 570-271-5251
Uniontown
UPMC Uniontown Hospital Radiation Oncology
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
Washington
UPMC Washington Hospital Radiation Oncology
Status: COMPLETED
Contact: Alison Rager Sehgal
Phone: 412-647-8073
West Reading
Reading Hospital
Status: COMPLETED
Contact: Terrence Paul Cescon
Phone: 610-988-9323
Wilkes-Barre
Geisinger Wyoming Valley / Henry Cancer Center
Status: COMPLETED
Contact: Joseph Joe Lukose Vadakara
Phone: 570-271-5251
Williamsport
UPMC Susquehanna
Status: COMPLETED
Contact: Warren Lewis Robinson
Phone: 800-598-4282
Wynnewood
Lankenau Medical Center
Status: COMPLETED
Contact: Albert S. DeNittis
Phone: 484-476-2649

South Carolina

Easley
Prisma Health Cancer Institute - Easley
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Gaffney
Gibbs Cancer Center-Gaffney
Status: COMPLETED
Contact: Asim Ranjan Pati
Phone: 800-486-5941
Greenville
Greenville Health System Cancer Institute-Andrews
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Prisma Health Cancer Institute - Butternut
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Prisma Health Cancer Institute - Eastside
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Prisma Health Cancer Institute - Faris
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Prisma Health Greenville Memorial Hospital
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Saint Francis Cancer Center
Status: COMPLETED
Contact: Robert D. Siegel
Phone: 864-255-1713
Saint Francis Hospital
Status: COMPLETED
Contact: Robert D. Siegel
Phone: 864-255-1713
Greer
Gibbs Cancer Center-Pelham
Status: COMPLETED
Contact: Asim Ranjan Pati
Phone: 800-486-5941
Prisma Health Cancer Institute - Greer
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Seneca
Prisma Health Cancer Institute - Seneca
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Spartanburg
Prisma Health Cancer Institute - Spartanburg
Status: COMPLETED
Contact: Jeffrey Kent Giguere
Phone: 864-241-6251
Spartanburg Medical Center
Status: COMPLETED
Contact: Asim Ranjan Pati
Phone: 800-486-5941
Union
MGC Hematology Oncology-Union
Status: COMPLETED
Contact: Asim Ranjan Pati
Phone: 800-486-5941

South Dakota

Rapid City
Rapid City Regional Hospital
Status: COMPLETED
Contact: Joshua Lukenbill
Phone: 605-716-3982
Sioux Falls
Avera Cancer Institute
Status: COMPLETED
Contact: Amy K. Krie
Phone: 888-634-7268
Sanford Cancer Center Oncology Clinic
Status: COMPLETED
Contact: Preston D. Steen
Phone: 701-234-6161
Sanford USD Medical Center - Sioux Falls
Status: COMPLETED
Contact: Preston D. Steen
Phone: 701-234-6161

Tennessee

Bristol
Wellmont Bristol Regional Medical Center
Status: COMPLETED
Contact: Asheesh Shipstone
Phone: 423-578-8538
Chattanooga
Memorial Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Hixson
Pulmonary Medicine Center of Chattanooga-Hixson
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Johnson City
Wellmont Medical Associates Oncology and Hematology-Johnson City
Status: COMPLETED
Contact: Asheesh Shipstone
Phone: 423-578-8538
Kingsport
Regional Cancer Center at Indian Path Community Hospital
Status: COMPLETED
Contact: Asheesh Shipstone
Phone: 423-578-8538
Wellmont Holston Valley Hospital and Medical Center
Status: COMPLETED
Contact: Asheesh Shipstone
Phone: 423-578-8538
Nashville
Meharry Medical College
Status: COMPLETED
Contact: Philip Edward Lammers
Phone: 615-327-5724
Ooltewah
Memorial GYN Plus
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119

Texas

Amarillo
The Don and Sybil Harrington Cancer Center
Status: COMPLETED
Contact: Stewart Allen Sharp
Phone: 806-359-4673
Dallas
Parkland Memorial Hospital
Status: COMPLETED
Contact: Robert Howard Collins
Phone: 214-648-7097
UT Southwestern / Simmons Cancer Center-Dallas
Status: COMPLETED
Contact: Robert Howard Collins
Phone: 214-648-7097
Lubbock
Covenant Medical Center-Lakeside
Status: COMPLETED
Contact: Donald Paul Quick
Phone: 806-725-8000
San Antonio
University Hospital
Status: COMPLETED
Contact: Anand Bhasker Karnad
Phone: 210-450-3800
University of Texas Health Science Center at San Antonio
Status: COMPLETED
Contact: Anand Bhasker Karnad
Phone: 210-450-3800

Vermont

Berlin
Central Vermont Medical Center / National Life Cancer Treatment
Status: COMPLETED
Contact: George Fuad Atweh
Phone: 802-656-8990
Burlington
University of Vermont Medical Center
Status: COMPLETED
Contact: George Fuad Atweh
Phone: 802-656-8990
University of Vermont and State Agricultural College
Status: COMPLETED
Contact: George Fuad Atweh
Phone: 802-656-8990

Virginia

Danville
Danville Regional Medical Center
Status: COMPLETED
Contact: Ashantice K. Higgins
Phone: 434-793-0044
Fredericksburg
Fredericksburg Oncology Inc
Status: CLOSED_TO_ACCRUAL
Contact: Rex B. Mowat
Phone: 800-444-3561
Hematology Oncology Associates of Fredericksburg Inc
Status: COMPLETED
Contact: Beata Holkova
Phone: 804-628-1939
Lynchburg
Centra Lynchburg Hematology-Oncology Clinic Inc
Status: COMPLETED
Contact: Beata Holkova
Phone: 804-628-1939
Martinsville
Sovah Health Martinsville
Status: COMPLETED
Contact: Sreedhar Katragadda
Phone: 276-666-7827
Norton
Southwest VA Regional Cancer Center
Status: COMPLETED
Contact: Asheesh Shipstone
Phone: 423-578-8538
Richmond
Virginia Cancer Institute
Status: COMPLETED
Contact: Beata Holkova
Phone: 804-628-1939
Virginia Commonwealth University / Massey Cancer Center
Status: COMPLETED
Contact: Beata Holkova
Phone: 804-628-1939
South Hill
VCU Community Memorial Health Center
Status: COMPLETED
Contact: Beata Holkova
Phone: 804-628-1939

Washington

Aberdeen
Providence Regional Cancer System-Aberdeen
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Anacortes
Cancer Care Center at Island Hospital
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Auburn
MultiCare Auburn Medical Center
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Bainbridge Island
Virginia Mason Bainbridge Island Medical Center
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Bellevue
Overlake Medical Center
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Swedish Cancer Institute-Eastside Oncology Hematology
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Bellingham
PeaceHealth Saint Joseph Medical Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Bremerton
Harrison HealthPartners Hematology and Oncology-Bremerton
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Harrison Medical Center
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Burien
Highline Medical Center-Main Campus
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Centralia
Providence Regional Cancer System-Centralia
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Edmonds
Swedish Cancer Institute-Edmonds
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Enumclaw
Saint Elizabeth Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Everett
Providence Regional Cancer Partnership
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Federal Way
Saint Francis Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Virginia Mason Federal Way Medical Center
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Gig Harbor
MultiCare Gig Harbor Medical Park
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Tacoma / Valley Radiation Oncology Centers-Gig Harbor
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Issaquah
Swedish Cancer Institute-Issaquah
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Kennewick
Northwest Cancer Clinic
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Lacey
Providence Regional Cancer System-Lacey
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Lakewood
Saint Clare Hospital
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Longview
PeaceHealth Saint John Medical Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Lynnwood
Virginia Mason Lynnwood Medical Center
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Port Townsend
Jefferson Healthcare
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Poulsbo
Harrison HealthPartners Hematology and Oncology-Poulsbo
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Peninsula Cancer Center
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Puyallup
MultiCare Good Samaritan Hospital
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Tacoma / Valley Radiation Oncology Centers-Puyallup
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Seattle
Fred Hutchinson Cancer Research Center
Status: COMPLETED
Contact: Mazyar Shadman
Phone: 800-422-6237
Kaiser Permanente Washington
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Minor and James Medical PLLC
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Pacific Gynecology Specialists
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Seattle Cancer Care Alliance
Status: COMPLETED
Contact: Mazyar Shadman
Phone: 800-422-6237
Swedish Medical Center-Ballard Campus
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Swedish Medical Center-First Hill
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
University of Washington Medical Center
Status: COMPLETED
Contact: Mazyar Shadman
Phone: 800-422-6237
Virginia Mason Medical Center
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Shelton
Providence Regional Cancer System-Shelton
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Spokane
Evergreen Hematology and Oncology PS
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
MultiCare Deaconess Cancer and Blood Specialty Center - Downtown
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Spokane Valley
MultiCare Deaconess Cancer and Blood Specialty Center - Valley
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Tacoma
Franciscan Research Center-Northwest Medical Plaza
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
MultiCare Tacoma General Hospital
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Northwest Medical Specialties PLLC
Status: COMPLETED
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Northwest NCI Community Oncology Research Program
Status: CLOSED_TO_ACCRUAL
Contact: John A. Keech
Phone: 253-403-2394
Tacoma / Valley Radiation Oncology Centers-Jackson Hall
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Tacoma / Valley Radiation Oncology Centers-Saint Joe's
Status: COMPLETED
Contact: John A. Keech
Phone: 253-403-2394
Vancouver
PeaceHealth Southwest Medical Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Walla Walla
Providence Saint Mary Regional Cancer Center
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Yakima
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412
Yelm
Providence Regional Cancer System-Yelm
Status: COMPLETED
Contact: Keith S. Lanier
Phone: 503-215-6412

West Virginia

Bridgeport
United Hospital Center
Status: COMPLETED
Contact: Abraham Sebastian Kanate
Phone: 304-293-2745
Martinsburg
WVUH-Berkely Medical Center
Status: COMPLETED
Contact: Abraham Sebastian Kanate
Phone: 304-293-2745
Morgantown
West Virginia University Healthcare
Status: COMPLETED
Contact: Abraham Sebastian Kanate
Phone: 304-293-2745
Parkersburg
Camden Clark Medical Center
Status: COMPLETED
Contact: Abraham Sebastian Kanate
Phone: 304-293-2745

Wisconsin

Antigo
Langlade Hospital and Cancer Center
Status: COMPLETED
Contact: Hamied R. Rezazadeh
Phone: 877-405-6866
Burlington
Aurora Cancer Care-Southern Lakes VLCC
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Chippewa Falls
Marshfield Clinic-Chippewa Center
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Eau Claire
HSHS Sacred Heart Hospital
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Marshfield Clinic Cancer Center at Sacred Heart
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Fond Du Lac
Aurora Health Center-Fond du Lac
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Germantown
Aurora Health Care Germantown Health Center
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Grafton
Aurora Cancer Care-Grafton
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Green Bay
Aurora BayCare Medical Center
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Bellin Memorial Hospital
Status: COMPLETED
Contact: Hassan I. Tahsildar
Phone: 920-435-8326
Green Bay Oncology Limited at Saint Mary's Hospital
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Green Bay Oncology at Saint Vincent Hospital
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Saint Vincent Hospital Cancer Center Green Bay
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Saint Vincent Hospital Cancer Center at Saint Mary's
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Janesville
Mercyhealth Hospital and Cancer Center - Janesville
Status: COMPLETED
Contact: Emily Gray Robinson
Phone: 800-928-1103
Kenosha
Aurora Cancer Care-Kenosha South
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
La Crosse
Gundersen Lutheran Medical Center
Status: COMPLETED
Contact: Kurt Oettel
Phone: 608-775-2385
Ladysmith
Marshfield Clinic - Ladysmith Center
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Manitowoc
Holy Family Memorial Hospital
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Marinette
Aurora Bay Area Medical Group-Marinette
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Marshfield
Marshfield Medical Center
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Marshfield Medical Center-Marshfield
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Milwaukee
Aurora Cancer Care-Milwaukee
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Aurora Saint Luke's Medical Center
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Aurora Sinai Medical Center
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Medical College of Wisconsin
Status: COMPLETED
Contact: Laura Christian Michaelis
Phone: 414-805-4380
Minocqua
Marshfield Clinic-Minocqua Center
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Mukwonago
ProHealth D N Greenwald Center
Status: COMPLETED
Contact: Timothy Robert Wassenaar
Phone: 262-928-5539
New Richmond
Cancer Center of Western Wisconsin
Status: COMPLETED
Contact: Joseph W. Leach
Phone: 952-993-1517
Oconomowoc
ProHealth Oconomowoc Memorial Hospital
Status: COMPLETED
Contact: Timothy Robert Wassenaar
Phone: 262-928-5539
Oconto Falls
Saint Vincent Hospital Cancer Center at Oconto Falls
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Oshkosh
Vince Lombardi Cancer Clinic - Oshkosh
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Racine
Aurora Cancer Care-Racine
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Rhinelander
Ascension Saint Mary's Hospital
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Saint Mary's Hospital
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Rice Lake
Marshfield Medical Center-Rice Lake
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Sheboygan
HSHS Saint Nicholas Hospital
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Vince Lombardi Cancer Clinic-Sheboygan
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Stevens Point
Ascension Saint Michael's Hospital
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Sturgeon Bay
Green Bay Oncology - Sturgeon Bay
Status: COMPLETED
Contact: Brian Leslie Burnette
Phone: 800-432-6049
Summit
Aurora Medical Center in Summit
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Two Rivers
Vince Lombardi Cancer Clinic-Two Rivers
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Waukesha
Aurora Cancer Care-Waukesha
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
ProHealth Waukesha Memorial Hospital
Status: COMPLETED
Contact: Timothy Robert Wassenaar
Phone: 262-928-5539
UW Cancer Center at ProHealth Care
Status: COMPLETED
Contact: Timothy Robert Wassenaar
Phone: 262-928-5539
Wausau
Aspirus Regional Cancer Center
Status: COMPLETED
Contact: Hamied R. Rezazadeh
Phone: 877-405-6866
Marshfield Clinic-Wausau Center
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Wauwatosa
Aurora Cancer Care-Milwaukee West
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
West Allis
Aurora West Allis Medical Center
Status: COMPLETED
Contact: Rubina Qamar
Phone: 888-709-2080
Weston
Ascension Saint Clare's Hospital
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Diagnostic and Treatment Center
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Marshfield Clinic - Weston Center
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457
Wisconsin Rapids
Aspirus UW Cancer Center
Status: COMPLETED
Contact: Hamied R. Rezazadeh
Phone: 877-405-6866
Marshfield Clinic - Wisconsin Rapids Center
Status: COMPLETED
Contact: Ali W. Bseiso
Phone: 715-389-4457

Wyoming

Casper
Rocky Mountain Oncology
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Cheyenne
Cheyenne Regional Medical Center-West
Status: COMPLETED
Contact: Keren Sturtz
Phone: 303-777-2663
Cody
Big Horn Basin Cancer Center
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Billings Clinic-Cody
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Sheridan
Welch Cancer Center
Status: COMPLETED
Contact: Benjamin T. Marchello
Phone: 800-648-6274

PRIMARY OBJECTIVES:

I. To evaluate the ability of Ibrutinib-based induction therapy to prolong progression free survival (PFS) compared to standard fludarabine phosphate, cyclophosphamide, and rituximab (FCR) chemoimmunotherapy for younger patients with chronic lymphocytic leukemia (CLL).

SECONDARY OBJECTIVES:

I. Evaluate overall survival (OS) of patients based on treatment arm.

II. Monitor and assess toxicity of treatment with Ibrutinib-based induction relative to standard FCR chemotherapy.

III. To compare quality of life (QOL) in CLL patients during the first 6 months of treatment among patients receiving Ibrutinib-based induction therapy relative to standard FCR chemoimmunotherapy.

IV. To compare QOL over the long-term in CLL patients receiving continuous therapy using Ibrutinib to that of CLL patients who completed FCR therapy.

V. Determine the effect of pretreatment clinical and biological characteristics (e.g. disease stage, immunoglobulin heavy chain variable region gene [IGHV] mutation status, fluorescent in situ hybridization [FISH]) on clinical outcomes (e.g. complete response, PFS) of the different arms.

VI. Determine if the minimal residual disease (MRD) status as assessed by flow cytometry at different time points during and after treatment is an effective surrogate marker for prolonged PFS and overall survival.

VII. Compare the genetic abnormalities and dynamics of intra-clonal architecture of CLL patients before and after treatment with chemoimmunotherapy (CIT) and non-CIT approaches and explore relationships with treatment resistance.

VIII. Explore the effects of FCR and Ibrutinib-based therapy on T-cell immune function.

IX. Conduct confirmatory validation genotyping of single nucleotide polymorphisms (SNPs) associated with the efficacy and toxicity of fludarabine-based therapy as in a prior Eastern Cooperative Oncology Group (ECOG) genome-wide association study (GWAS) analysis in the E2997 trial.

X. Evaluate the ability of prognostic model that incorporates clinical and biologic characters to predict a response to therapy and clinical outcome (PFS, OS).

XI. Evaluate signaling networks downstream of the B-cell receptor in patients receiving Ibrutinib-based therapy.

XII. Collect relapse samples to study mechanisms of resistance to both FCR and Ibrutinib-based therapy.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM A: Patients receive ibrutinib orally (PO) once daily (QD) on days 1-28. Beginning course 2, patients also receive rituximab intravenously (IV) over 4 hours on day 1 (days 1 and 2 of course 2 only). Treatment repeats every 28 days for 7 courses. In the absence of disease progression, patients may continue ibrutinib PO QD.

ARM B: Patients receive rituximab as seen in Arm A and fludarabine phosphate IV over 30 minutes and cyclophosphamide IV over 30 minutes on days 1-3. Treatment repeats every 28 days for 6 courses.

After completion of study treatment, patients are followed up for 10 years.

Trial Phase Phase III

Trial Type Treatment

Lead Organization
ECOG-ACRIN Cancer Research Group

Principal Investigator
Tait D. Shanafelt

  • Primary ID E1912
  • Secondary IDs NCI-2014-00118, ECOG-E1912
  • Clinicaltrials.gov ID NCT02048813