This pilot clinical trial studies diffuse optical spectroscopic imaging in screening and measuring tumor dynamics and response in patients with breast cancer. Diffuse optical spectroscopic imaging may help doctors find breast cancer sooner, when it may be easier to treat.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT00540540.
PRIMARY OBJECTIVE:
I. To move towards developing a simple, rapid, hand-held optical screening device which will yield low resolution tissue functional information in breast tissue of human subjects that complements and enhances the detailed structural information obtained from x-ray mammography.
OUTLINE:
Participants undergo diffuse optical spectroscopic imaging (DOSI). Participants then breathe 15.5% oxygen for 10 minutes followed by DOSI and then breathe 100% oxygen for 10 minutes followed by DOSI. Participants may undergo imaging up to 5 times over 3 months.
Trial PhaseNo phase specified
Trial Typescreening
Lead OrganizationUC Irvine Health/Chao Family Comprehensive Cancer Center
Principal InvestigatorBruce J. Tromberg
