This pilot clinical trial studies optical spectroscopy in diagnosing patients with cervical cancer while undergoing loop electrosurgical excision procedure (LEEP) or colposcopy. New diagnostic procedures, such as optical spectroscopy, may be a less invasive method of finding cervical cancer.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT00900575.
Locations matching your search criteria
United States
North Carolina
Durham
Duke University Medical CenterStatus: Active
Contact: Nimmi Ramanujam
Phone: 919-660-5307
Durham Regional HospitalStatus: Active
Contact: Nimmi Ramanujam
Phone: 919-660-5307
PRIMARY OBJECTIVES:
I. To develop new diagnostic modalities based on optical spectroscopy (auto fluorescence, absorption, and scattering) and non-contact fluorescence imaging platform and test its performance for epithelial pre-cancer detection as an adjunct to gold standard histopathology from biopsy and/or LEEP specimens.
II. To apply these probes for the diagnosis of epithelial pre-cancers and cancers in the human cervix and demonstrate its diagnostic potential for cervical pre-cancers and cancers.
OUTLINE:
Patients undergo ultraviolet-visible (UV-VIS) diffuse reflectance spectroscopy (DRS) or fluorescence spectroscopy during LEEP or colposcopy procedure.
Trial PhaseNo phase specified
Trial Typediagnostic
Lead OrganizationDuke University Medical Center
Principal InvestigatorNimmi Ramanujam
