This pilot early phase I trial studies the use of short breast magnetic resonance imaging (SBMRI) in screening patients at high risk for breast cancer. SBMRI may help doctors find breast cancer sooner, when it may be easier to treat.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT02590458.
PRIMARY OBJECTIVE:
I. To estimate sensitivity of a short breast magnetic resonance imaging (MRI) (BMRI) technique tailored for screening high-risk patients to standard BMRI technique for high risk breast screening.
SECONDARY OBJECTIVE:
I. Test patient throughput, acceptance and comfort compared to existing BMRI protocol.
EXPLORATORY OBJECTIVE:
I. To investigate technical image quality of dynamic contrast-enhanced (DCE)-MRI and T2-weighted (T2W) sequences compared to standard of care (SOC) axial dynamic breast MRI protocol.
OUTLINE:
Patients undergo standard of care MRI over 30-60 minutes followed by short BMRI over approximately 10 minutes 1-7 days after.
After completion of study, patients are followed up for 1 year.
Lead OrganizationM D Anderson Cancer Center
Principal InvestigatorMarion Elizabeth Scoggins
