Intraoperative Imaging using OTL38 in Diagnosing Patients with Lung or Pleura Nodules Undergoing Surgery

This phase II trial studies intraoperative imaging using fluorescent imaging ligand OTL38 (OTL38) in diagnosing patients with lung or pleura nodules undergoing surgery. Drugs, such as OTL38, attach to the cancer and "mark" it. During surgery, the surgeons hold a camera system over the nodule that will excite OTL38. Imaging during surgery may cause the nodule to glow, thus "marking" the cancer and making it easier for surgeons to remove.

Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT02602119.

Trial PhasePhase II

Trial Typediagnostic

Lead OrganizationUniversity of Pennsylvania/Abramson Cancer Center

Principal InvestigatorSunil Singhal

• Primary IDUPCC 04515
• Secondary IDsNCI-2016-00753
• ClinicalTrials.gov IDNCT02602119