This trial studies how well near-infrared fluorescence imaging works in identifying lymph nodes in patients with head and neck cancer undergoing biopsy. Near-infrared fluorescence imaging may help surgeons identify the lymph nodes in patients with head and neck cancer undergoing a standard biopsy procedure.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT03297957.
PRIMARY OBJECTIVES:
I. To determine the feasibility of using a novel hands-free goggle device to detect sentinel lymph nodes during sentinel lymph node biopsy for head and neck malignancies using indocyanine green (ICG) fluorescence.
II. To determine if there is contrast between sentinel lymph nodes and surrounding tissues using this device.
OUTLINE:
Patients receive ICG intratumorally (IT) and undergo standard sentinel lymph node biopsy and near-infrared fluorescence imaging over 1.5 hours.
After completion of study, patients are followed up at 3 hours.
Trial PhaseNo phase specified
Trial Typediagnostic
Lead OrganizationSiteman Cancer Center at Washington University
Principal InvestigatorRyan S. Jackson
