Omega-3 Fatty Acid in Preventing Breast Cancer in Premenopausal Women Considering Future Pregnancy

Inclusion Criteria

• Women must be pre-menopausal as defined as having intact ovaries with regular menses or if not menstruating, have a premenopausal status confirmed by serum follicle-stimulating hormone (FSH) and estradiol
• Women must be considered at high risk for breast cancer based on family history (first or second degree relative diagnosed with breast cancer under the age of 60), prior precancerous biopsy or a 5-year Gail model risk estimate of >= 1.7% or 10-year Tyrer-Cuzick risk of 2 x population risk as listed in the model
• Women must indicate that they are still considering future pregnancy and childbearing
• Women must be one year from pregnancy and breast-feeding
• Women must be willing to take supplemental omega-3 fatty acids provided by the study

Exclusion Criteria

• Women actively undergoing in-vitro fertilization or fertility treatments are excluded
• Women currently pregnant or breast-feeding at time of study consent
• Women with an active malignancy
• Women on anticoagulation
• Women with bilateral breast implants or tram flap reconstruction
• Women who have had radiation to both breasts
• Women with current mammographic or clinical breast exam mass which is suspicious for breast cancer and malignancy has not been ruled out