Fluorine F 18 Fluorthanatrace PET/CT in Measuring PARP-1 Expression in Patients with Prostate Cancer

Inclusion Criteria

• Participants will be ≥ 18 years of age
• Biopsy proven prostate cancer
• Must meet one of the following criteria: * At least two tissue cores containing at least 50% tumor (per pathology report) OR * At least one lesion that is 1 cm or greater in size by standard imaging (e.g. ultrasound, magnetic resonance imaging [MRI], CT). Only one type of imaging is required to show a lesion of 1 cm or greater in order for the patient to be eligible to participate in this study
• Recommended for clinically indicated radical prostatectomy or oligometastectomy
• Willing to allow use or collection of pathology tissue for the purposes of research from either clinical biopsy or surgical procedure (if adequate tissue is available)
• Participants must be informed of the investigational nature of this study and be willing to provide written informed consent and participate in this study in accordance with institutional and federal guidelines prior to study-specific procedures

Exclusion Criteria

• Inability to tolerate imaging procedures in the opinion of an investigator or treating physician
• Serious or unstable medical or psychological conditions that, in the opinion of the investigator, would compromise the subject’s safety or successful participation in the study