HIIT before Surgery in Improving Outcomes in Patients with Endometrial Cancer

Inclusion Criteria

• Patients with a diagnosis of endometrioid histology cancer or complex endometrial hyperplasia who are to undergo hysterectomy and staging.
• Body mass index of 30-50 kg/m^2.
• Presumed clinically early stage disease (disease confined to uterus only)
• Have access to a smart phone.
• Have access to email.
• Agree to visit the exercise and sport science laboratory prior to surgery for baseline testing if enrollment procedures cannot be done on the same day.
• Agree to visit clinic 2 to 4 weeks after surgery for standard of care (SOC) follow-up and post surgery visit, or willing to return to exercise and sport science laboratory 2 to 4 weeks post-surgery.

Exclusion Criteria

• Meets American College of Sports Medicine Guidelines for physical activity (150 minutes / week).
• Currently doing HIIT.
• Hospitalization for a stroke, heart attack, or heart failure, or had surgery for blocked arteries in the past 3 months.
• Active diagnosis of psychosis or current uncontrolled substance abuse disorder.
• Insulin-dependent diabetes.
• Currently in another EC intervention.
• Severe dementia or other memory loss condition.
• Severe mental health disorder.
• Severely impaired hearing or speech.
• Inability to speak English.
• Musculoskeletal or neuromuscular condition that limits physical activity.
• Any condition, in the opinion of the investigators, which would prohibit safe participation.