Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy

This trial studies the metabolism of kidney or urothelial cancer in patients undergoing surgical removal (resection) and/or biopsy. Metabolism is the term used to describe how cells take up different nutrients and convert them to energy and materials needed for cell growth. In cancer, metabolism is hijacked to support the needs of cancer cells. Cancer cells can use multiple nutrients in the blood to fuel their growth, but it is not yet known what materials cancer cells make with those nutrients in patients. This study may help researchers understand how kidney cancers change their metabolism to adapt, grow, and survive in patients. The researchers may use the knowledge from this study to support development of therapies that target metabolic adaptations of cancer cells, and to develop new, non-invasive imaging techniques that can be used to monitor tumor growth.

Additional locations may be listed on ClinicalTrials.gov for NCT04623502.

Trial PhaseNo phase specified

Trial TypeNot provided by clinicaltrials.gov

Lead OrganizationUT Southwestern/Simmons Cancer Center-Dallas

Principal InvestigatorVitaly Margulis

• Primary IDSCCC-05219; STU-2019-1061
• Secondary IDsNCI-2019-08259
• ClinicalTrials.gov IDNCT04623502