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Immunotherapy with Nivolumab Before and after Surgery for the Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

Trial Status: active

This phase I trial studies the side effects of nivolumab before and after surgery in treating children and young adults with high grade glioma that has come back (recurrent) or is increasing in scope or severity (progressive). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.