An Investigational Scan (18F-DCFPyL PET/CT) for the Detection of PSMA in Patients with HER2-Negative, Androgen Receptor Positive Breast Cancer

This phase II trial studies how well 18F-DCFPyL PET/CT scan works in detecting a protein called PSMA in patients with HER2-negative, androgen receptor positive breast cancer. PET takes pictures of the inside the body using a special substance or “tracer” that is injected through a needle in the arm. 18F-DCFPyL is the tracer that is used in this research. PET images are made when the scanner detects the levels of the tracer throughout the entire body. CT scans take 3-dimensional pictures of inside the body using x-rays. Currently, PET and CT images are collected at the same time because the CT scan provides images of the body’s anatomy and the PET scan shows where in the body the tracer is more concentrated. This trial may help researchers develop novel ways to detect and treat breast cancer.

Additional locations may be listed on ClinicalTrials.gov for NCT04573231.

Trial PhasePhase II

Trial Typediagnostic

Lead OrganizationUniversity of Wisconsin Carbone Cancer Center - University Hospital

Principal InvestigatorSteve Yoon-Ho Cho

• Primary IDUW20035
• Secondary IDsNCI-2020-07434
• ClinicalTrials.gov IDNCT04573231