LCAM for Hereditary Cancer Screening in Patients with Cancer, IMAGINE Study

Inclusion Criteria

• PHASE 1: Age >= 18 years as per self-report
• PHASE 1: Current or previous diagnosis of breast, ovarian, pancreatic, or prostate cancer as per self-report
• PHASE 1: Self-identification as Black, Latino, and/or neither Black nor Latino (i.e., non-Latino non-Black)
• PHASE 1: Fluency in English, Haitian Creole, or Spanish as per self-report (for Spanish, we will attempt to recruit a cohort representing a variety of regions where Spanish is spoken, as informed by current data from participating sites, to achieve neutrality in the language). Fluency is defined as an answer of “well” or “very well” on the screening questions for spoken and reading ability
• PHASE 2: Age >= 18 years as per the medical record
• PHASE 2: Current or previous diagnosis of breast, colorectal, ovarian, pancreatic, or prostate cancer meeting at least one of the applicable criteria for the cancer type as per the medical record and/or clinician referral
• PHASE 2: Breast cancer criteria: * Any diagnosis age 65 or younger; * Diagnosis of triple negative breast cancer at any age; * Multiple primary breast cancers at any age; * Under consideration for poly (ADP-ribose) polymerase (PARP) therapy; * Any family history (1st, 2nd, or 3rd degree relatives) of ovarian or pancreas cancer, or 1 relative with breast cancer who meets the above criteria, or 2 relatives with breast cancer at any age; or clinician discretion
• PHASE 2: Colorectal cancer criteria: * Colorectal cancer
• PHASE 2: Ovarian cancer criteria: * Invasive ovarian cancer
• PHASE 2: Pancreatic cancer criteria: * Pancreatic adenocarcinoma
• PHASE 2: Prostate cancer criteria: * Metastatic prostate cancer; * High-risk prostate cancer (pending pathology definition)
• PHASE 2: Fluency in English, Haitian Creole, or Spanish as per self-report. Fluency is defined as an answer of “well” or “very well” on the screening questions for spoken ability
• PHASE 2: No prior cancer genetic counseling or germline testing for cancer risk as per self-report, clinician's note, and/or no clinical documentation

Exclusion Criteria

• PHASE 1: Individuals of impaired decision-making capacity as per a clinician’s or consenting professionals' judgment
• PHASE 1: Subjects who indicate level of fluency as “not at all” or “not well”
• PHASE 2: Individuals of impaired decision-making capacity as per a clinician’s or consenting professional’s judgment
• PHASE 2: Subjects who indicate level of spoken fluency as “not at all” or “not well”