Navigation Systems (3D Slicer and the Siemens Monaco System) to Increase Efficiency of Surgery in Patients with Urologic Cancers

Inclusion Criteria

• Signed written informed consent before any trial-related procedure is undertaken that is not part of the standard patient management
• Subjects aged >= 18 years. Selected patients must have a confirmed or suspected diagnosis of disease in urologic regions of interest, with scheduled confirmatory surgical biopsy.
• Subjects must have had computed tomography (CT), positron emission tomography (PET) or magnetic resonance (MR) of acceptable quality at Brigham and Women’s Hospital within the past year.
• Subjects must also be scheduled to undergo lymph node dissection for a urologic cancer or organ removal of any of the within the following urologic regions of interest: bladder, prostate, testicle, ureter, kidney, urethra, penis, and scrotum
• Subjects must also be scheduled to undergo a laparoscopic lymph node dissection and/or a urologic organ removal within the Advanced Multimodality Image-Guided Operating (AMIGO) operating room (OR) at Brigham and Women’s Hospital

Exclusion Criteria

• Severely impaired renal function with an estimated glomerular filtration rate (EGFR) < 30 mL/min/body surface area
• Evidence of any significant, uncontrolled comorbid condition that could affect compliance with the protocol or interpretation of the results, which is to be judged at the discretion of the principal investigator (PI)
• History of hypersensitivity or other contraindication to contrast media
• Contraindication to general anesthesia
• Pregnancy