Self-Collection Method for Human Papillomavirus (HPV) Screening for Cervical Cancer

Inclusion Criteria

• Adults aged 25-65 years old
• Appointment at Mayo Clinic Rochester in Gynecology Colposcopy Clinic or ICS (integrated community specialty) Colposcopy Clinic (will always include a speculum exam)
• Appointment at Mayo Clinic Rochester in Gynecology Clinic for indication that will already include a speculum exam (e.g., cervical cancer screening or IUD insertion)

Exclusion Criteria

• Excluded if self-reported as currently menstruating, pregnant, or within 3 months following pregnancy
• Excluded if no cervix (history of total hysterectomy)
• Excluded if moderate to heavy vaginal bleeding on the day of the visit
• Excluded if reason for visit in Gynecology Clinic is abnormal vaginal discharge
• Exclude patients who are on Gynecology Colposcopy Clinic for LEEP (loop electrosurgical excision procedure)
• Exclude if any use of over-the-counter or prescription vaginal cream for vaginal infection or prescription vaginal estrogen cream for at least two days before using the Evalyn Brush (vaginal contraceptives, condoms and water-based lubricants can be used as normal)