A Study to Examine Mindfulness Training to Improve Mental Health and Well-being in Younger Breast Cancer Survivors, HEAL-ABC Trial

Inclusion Criteria

• The participant must provide study-specific informed consent prior to registration and, for participants treated in the United States (U.S.), authorization permitting release of personal health information
• The participant must have been ≥ 18 and < 51 years of age at the time of breast cancer diagnosis and be within 5 years of their breast cancer diagnosis
• The participant must have a first-time diagnosis of non-metastatic breast cancer which is stage 0, I, II, or III
• The participant must have a score of ≥ 5 and ≤ 14 on the Patient Health Questionnaire-8 item (PHQ-8)
• Participants must have completed all primary breast cancer treatments at least 6 months prior to registration * Note: Primary treatments include surgery, radiation therapy, adjuvant chemotherapy, and targeted therapies (e.g., poly [ADP-ribose] polymerase [PARP] inhibitors, CDK4/6 inhibitors, trastuzumab emtansine [TDM-1], pertuzumab, or immunotherapy)). Participants may still be taking adjuvant therapy with trastuzumab or adjuvant endocrine therapy or completing minor reconstructive surgery
• The participant must be able to understand, speak, read, and write in English or Spanish
• Participant must be willing to participate in a 6-week program to receive training in mindfulness
• Participant must be able to use a smartphone, tablet, or other digital device
• Sex assigned at birth must be female

Exclusion Criteria

• Patient Health Questionnaire-8 item (PHQ-8) score of < 5 or > 14
• Any history or current evidence of recurrent or metastatic breast cancer
• Current or past history of another cancers. Participants with a history of only non-melanoma skin cancer or in situ cervical cancer without chemotherapy treatment would be eligible
• Currently pregnant or planning to become pregnant in the near future
• More than 5 years since diagnosis of breast cancer
• Participants who are enrolled in other cancer control or behavioral intervention trials that require frequent assessments or training activities