This clinical trial tests how well a sugary drink reduction program, iSIPsmarter, works to educate people at risk for developing colorectal cancer. Colorectal cancer is the second most common cancer in the United States and racial disparities in this disease are well documented and widening. While the overall incidence and mortality rates of colorectal cancer have steadily declined in the United States, these rate reductions have been much slower among African Americans. Drinking beverages sweetened with high fructose corn syrup has increased along with early-onset colorectal cancer. This suggests that there might be a potential link between sugary drinks and colorectal cancer. African Americans have the highest sugary drink intake among all racial/ethnic groups. Researchers at the University of Virginia are looking at how overconsumption of sugary drinks is related to the development of colorectal polyps and are especially interested in how sugary drinks might contribute to the observed racial disparities in colorectal cancer. iSIPsmarter is a websire designed to provide tailored instructions about how to reduce sugary drinks. A behavioral and lifestyle program iSIPsmarter may help reduce the risk of developing colorectal cancer.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT06669923.
Locations matching your search criteria
United States
Virginia
Charlottesville
University of Virginia Cancer CenterStatus: Active
Contact: Li Li
Phone: 434-982-3975
PRIMARY OBJECTIVE:
I. Feasibility of administration of iSIPsmarter to high-risk patients.
SECONDARY OBJECTIVES:
I. Evaluate the role of sugar-sweetened beverages in racial disparities of side-specific colon neoplasia.
II. Determine the efficacy of iSIPsmarter intervention.
OUTLINE:
BASELINE STUDY: Patients complete questionnaires, an interview, and anthropometrical measurements, as well as undergo blood, stool, and colorectal tissue sample collection on study.
FOLLOW-UP STUDY: Patients are randomized to 1 of 2 groups.
GROUP I: Patients receive web-based patient education to learn about risk and protective factors in various cancers and connecting to cancer information resources over 9 weeks.
GROUP II: Patients participate in the web-based iSIPsmarter program to learn about sugary drink information presented in an interactive design and metered out over the course of 6 core modules over 45-60 minutes each over 9 weeks.
After completion of study intervention, patients are followed up at 6 and 18 months.
Trial PhaseNo phase specified
Trial Typeprevention
Lead OrganizationUniversity of Virginia Cancer Center
Principal InvestigatorLi Li
