A Study of Atezolizumab in Combination With Carboplatin Plus (+) Nab-Paclitaxel Compared With Carboplatin+Nab-Paclitaxel in Participants With Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Inclusion Criteria

• Inclusion Criteria: - Eastern Cooperative Oncology Group performance status of 0 or 1 - Histologically or cytologically confirmed, Stage IV non-squamous NSCLC - Participants with no prior treatment for Stage IV non-squamous NSCLC - Previously obtained archival tumor tissue or tissue obtained from fresh biopsy at screening - Measurable disease, as defined by RECIST v1.1 - Adequate hematologic and end organ function Exclusion Criteria: Cancer-Specific Exclusions: - Active or untreated central nervous system metastases - Malignancies other than NSCLC within 5 years prior to randomization, with the exception of those with a negligible risk of metastasis or death treated with expected curative outcome General Medical Exclusions: - Pregnant or lactating women - History of autoimmune disease - History of idiopathic pulmonary fibrosis, organizing pneumonia, drug-induced pneumonitis, idiopathic pneumonitis, or evidence of active pneumonitis on screening chest computed tomography scan. History of radiation pneumonitis in the radiation field (fibrosis) is permitted - Positive test for human immunodeficiency virus - Active hepatitis B or hepatitis C - Severe infection within 4 weeks prior to randomization - Significant cardiovascular disease - Illness or condition that interferes with the participant's capacity to understand, follow and/or comply with study procedures Exclusion Criteria Related to Medications: - Prior treatment with cluster of differentiation 137 agonists or immune checkpoint blockade therapies, anti-programmed death-1, and anti-PD-L1 therapeutic antibodies