Goal2Quit and Nicotine Replacement Therapy for Smoking Cessation

PRIMARY OBJECTIVES:

I. Develop Goal2Quit consistent with the behavioral activation (BA) for smoking cessation manual and will complete usability testing of the application (app) with depressed smokers (N=10) engaged with primary care.

II. Refine the app and preliminarily test the integrated intervention via a single-arm feasibility test (N=10) followed by individual interviews to address potential pitfalls.

III. Conduct an randomized controlled trial (RCT) (N=150, followed for 12 weeks) of Goal2Quit + nicotine replacement therapy (NRT) sampling as compared to treatment as usual (TAU) among primary care engaged adults with primary objective to provide effect size estimates for a larger RCT.

OUTLINE:

USABILITY TESTING: Patients are audio and video recorded while using Goal2Quit.

FEASIBILITY TESTING: Patients receive a code to download Goal2Quit, use the app for over 10 minutes, and ask questions about its functionality. Patients also receive a 2-week starter kit sample of NRT (patch and lozenge), educational materials suggesting that Goal2Quit be used daily to quit smoking, a handout for detailing assessments and payment schedules for assessments, and a National Cancer Institute (NCI) ''Clearing the Air'' booklet which includes information on quitting smoking.

SMALL-SCALE RCT: Patients are randomized to 1 of 2 arms.

ARM I (GOAL2QUIT + NRT): Patents receive their intervention in the same manner as feasibility testing

participants.

ARM II (TAU): Patients receive treatment as usual, consisting of a NCI ''Clearing the Air'' booklet which includes information on quitting smoking, and information on study participation.

After initiation of study, patients are followed up weekly for 8 weeks, and at 12 weeks.