This clinical trial studies the use of a smoking cessation intervention (contingency management) to promote smoking abstinence in patients who are about to undergo surgery for cancer. Contingency management involves receiving financial payment for cigarette abstinence. Information from this study may help researchers find a better method to promote smoking abstinence in patients with cancer.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT04605458.
PRIMARY OBJECTIVE:
I. To compare tobacco abstinence rates in the preoperative period for cancer patients who smoke and receive a contingency management (CM) intervention (monetary payment contingent on abstinent breath carbon monoxide [CO] + counseling + nicotine replacement therapy [NRT]) versus a counseling and nicotine replacement therapy (C+NRT) intervention (breath CO monitoring with no payment for abstinence + counseling + NRT).
SECONDARY OBJECTIVE:
I. To examine rates of tobacco abstinence at 3- and 6-months after surgery.
EXPLORATORY OBJECTIVES:
I. To examine rates of preoperative complications (i.e., wound infections, respiratory complications).
II. To examine clinical moderators of treatment to determine which subgroups are most likely to respond to the CM intervention.
III. To examine cost-effectiveness of the intervention.
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients participate in 3 counseling sessions over 15-20 minutes each over 10 days to 3 weeks and receive NRT lozenges or patches. Patients also undergo CO breath test monitoring three times per week.
ARM II: Patients participate in counseling sessions and NRT as in arm I. Patients undergo CO breath test monitoring three times per week and receive financial compensation based on CO breath test results.
After completion of study intervention, patients are followed up at 3 and 6 months.
Trial PhaseNo phase specified
Trial Typeprevention
Lead OrganizationMedical University of South Carolina
Principal InvestigatorBenjamin Toll
