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Publications from the Nanotechnology Characterization Lab

Recent Publications 

Target-specific nanoparticle polyplex down-regulates mutant Kras to prevent pancreatic carcinogenesis and halt tumor progression.
Smith JP, Chen W, Shivapurkar N, Gerber M, Tucker RD, Kallakury B, Dasa SSK, Kularatne RN, Stern ST. 
Int J Mol Sci. 2023; 24(1): 752. [PubMed Abstract]

Nanocomplexes of doxorubicin and DNA fragments for efficient and safe cancer chemotherapy.
Mohammad SN, Choi YS, Chung JY, Cedrone E, Neun BW, Dobrovolskaia MA, Yang X, Guo W, Chew YC, Kim J, Baek S, Kim IS, Fruman DA, Kwon YJ.
J Control Release. 2023; 354: 91-108. [PubMed Abstract]

Innate immune stimulation using 3D wireframe DNA origami.
Du RR, Cedrone E, Romanov A, Falkovich R, Dobrovolskaia MA, Bathe M.
ACS Nano. 2022; 16(12): 20340-20352. [PubMed Abstract]

Trends and patterns in cancer nanotechnology research: A survey of NCI's caNanoLab and Nanotechnology Characterization Laboratory.
Ke W, Crist RM, Clogston JD, Stern ST, Dobrovolskaia MA, Grodzinski P, and Jensen MA.
Adv Drug Deliv Rev. 2022; 114591. [PubMed Abstract]

Lessons learned from immunological characterization of nanomaterials at the Nanotechnology Characterization Laboratory.
Dobrovolskaia MA.
Front Immunol. 2022; 13: 984252. [PubMed Abstract]

Artificial immune cell, AI-cell, a new tool to predict interferon production by peripheral blood monocytes in response to nucleic acid nanoparticles.
Chandler M, Jain S, Halman J, Hong E, Dobrovolskaia MA, Zakharov AV, Afonin KA.
Small. 2022, e2204941. [PubMed Abstract]

Cancer nanomedicine.
Bhatia SN, Chen X, Dobrovolskaia MA, Lammers T.
Nature Reviews Cancer. 2022; 22(10): 550-556. [PubMed Abstract]

Locking and unlocking thrombin function using immunoquiescent nucleic acid nanoparticles with regulated retention in vivo.
Ke W, Chandler M, Cedrone E, Saito RF, Rangel MC, de Souza Junqueira M, Wang J, Shi D, Truong N, Richardson M, Rolband LA, Dreau D, Bedocs P, Chammas R, Dokholyan NV, Dobrovolskaia MA, Afonin KA.
Nano Letters. 2022; 22(14): 5961-5972. [PubMed Abstract]

The future of tissue-targeted lipid nanoparticle-mediated nucleic acid delivery.
Kularatne RN, Crist RM, Stern ST.
Pharmaceuticals. 2022; 15(7): 897. [PubMed Abstract]

Immunophenotyping: analytical approaches and role in preclinical development of nanomedicines.
Newton HS, Dobrovolskaia MA.
Adv Drug Deliv Rev. 2022; 185: 114281. [PubMed Abstract]

Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccines.
Szebeni J, Storm G, Ljubimova JY, Castells M, Phillips EJ, Turjeman K, Barenholz Y, Crommelin DJA, Dobrovolskaia MA.
Nat Nanotechnol. 2022; 17(4): 337-346. [PubMed Abstract]

Anhydrous nucleic acid nanoparticles for storage and handling at broad range of temperatures.
Tran AN, Chandler M, Halman J, Beasock D, Fessler A, McKeough RQ, Lam PA, Furr DP, Wang J, Cedrone E, Dobrovolskaia MA, Dokholyan NV, Trammell SR, Afonin KA.
Small. 2022; 18(13): e2104814. [PubMed Abstract]

To PEGylate or not to PEGylate: Immunological properties of nanomedicine's most popular component, polyethylene glycol and its alternatives.
Shi D, Beasock D, Fessler A, Szebeni J, Ljubimova JY, Afonin KA, Dobrovolskaia MA.
Adv Drug Deliv Rev. 2022; 180: 114079. [PubMed Abstract]

Critical review of nucleic acid nanotechnology to identify gaps and inform a strategy for accelerated clinical translation.
Afonin KA, Dobrovolskaia MA, Ke W, Grodzinski P, Bathe M.
Adv Drug Deliv Rev. 2022; 181: 114081. [PubMed Abstract]


For a more comprehensive list of NCL publications, visit our Web of Science bibliography page.


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