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Myelofibrosis and Essential Thrombocythemia Observational Study (MOST)
Trial Status: complete
The purpose of this prospective, longitudinal, noninterventional study is to describe
clinical characteristics, evolution of disease burden, and treatment patterns in patients
with select subcategories of essential thrombocythemia (ET) or myelofibrosis (MF).
Inclusion Criteria
MF cohort: Diagnosis of MF and low-risk using DIPSS risk categorization OR intermediate-1 risk by DIPSS by reason of age alone.
ET cohort: Diagnosis of ET and age ≥ 60 years OR history of thromboembolic events OR currently receiving ET-directed therapy (eg, hydroxyurea, anagrelide, interferon, busulfan, ruxolitinib, etc).
Willing and able to provide written informed consent.
Willing and able to complete patient assessment questionnaires either alone or with minimal assistance from a caregiver and/or trained site personnel.
Under the supervision of a physician for the current care of MF or ET.
Exclusion Criteria
Individuals who are participating in blinded investigational drug studies.
Individuals who are participating in Incyte investigational/interventional drug trials (company- or investigator-sponsored studies) until they have completed the 30-day end of study visit.
Life expectancy ≤ 6 months.
Diagnosis of secondary acute myeloid leukemia, myelodysplastic syndrome, chronic myelogenous leukemia, or secondary thrombocytosis.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT02953704.
Locations matching your search criteria
United States
Kansas
Kansas City
University of Kansas Cancer Center
Status: Active
Name Not Available
Westwood
University of Kansas Hospital-Westwood Cancer Center
Status: Active
Name Not Available
New Hampshire
Lebanon
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center