This randomized pilot clinical trial studies how well delaying the first cigarette works in changing brain activation in current smokers. Learning the practice-related brain activation may help to design more effective smoking cessation programs.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT03080844.
PRIMARY OBJECTIVES:
I. Identify the impact of practicing compared to not practicing delaying the first cigarette of the day on functional brain activation changes in the cognitive control and reward networks in response to smoking cues.
II. In the group practicing delaying the first cigarette of the day, examine the association between the amount of practice (i.e. amount of time delaying the first cigarette of the day) and functional brain activation changes in the cognitive control and reward networks in response to smoking cues.
SECONDARY OBJECTIVES:
I. Examine the association between practice related brain activation changes in the cognitive control and reward networks and individual differences (e.g. dependence, motivation, and gender).
OUTLINE: Participants are randomized into 1 of 2 groups.
GROUP I: Participants receive tips on how to resist the urge to smoke and practice progressively delaying the time to the first cigarette of the day over 2 weeks.
GROUP II: Participants receive tips on how to resist the urge to smoke and smoke as usual over 2 weeks.
Trial PhaseNo phase specified
Trial Typeprevention
Lead OrganizationUniversity of Kansas Cancer Center
Principal InvestigatorLaura Martin