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Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

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Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Pembrolizumab with and without Intra-operative Radiation Therapy in Treating Patients with Triple Negative Breast Cancer

Trial Status: closed to accrual

This phase I trial studies how well pembrolizumab works in treating patients with triple negative breast cancer with and without intra-operative radiation therapy. Immunotherapy with monoclonal antibodies, such as pembrolizumab may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Intra-operative radiation therapy involves radiation treatment aimed directly at a tumor during surgery. Giving pembrolizumab with intra-operative radiation therapy may work better in treating patients with triple negative breast cancer.