The Promoting Resilience in Stress Management Intervention in Reducing Anxiety and Depression in Adolescents and Young Adults with Cancer Undergoing Donor Stem Cell Transplant

Inclusion Criteria

• PATIENTS: Patient aged 12-17 years: has signed informed assent and their parent/legal guardian has signed informed consent for study participation
• PATIENTS: Patient aged 18-24 years: has signed informed consent for study participation
• PATIENTS: Receiving allogeneic hematopoietic cell transplantation (HCT) for treatment of malignancy at Seattle Cancer Care Alliance (Seattle Children’s Hospital and Fred Hutchinson Cancer Research Center) or Children’s Hospital Los Angeles (CHLA) * Within 4 weeks of their HCT date (“day zero”) (if prior, their planned HCT date)
• PATIENTS: Patient able to speak and read English language
• PATIENTS: Patient able to read in the English or Spanish language
• PATIENTS: Cognitively able to participate in interactive interviews
• HRV COMPONENT ONLY: Patient able to speak and read in English
• PATIENTS: Note: Concurrent parent participation is not required for adolescent and young adult (AYA) patient participation
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN SURVEY-COMPLETION: AYA child of parent or guardian agrees to participate in study
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN SURVEY-COMPLETION: AYA child participant provides verbal assent or verbal consent if 18 or over for parent or guardian to complete surveys
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN SURVEY-COMPLETION: One parent per patient parent dyad
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN SURVEY-COMPLETION: Parent/guardian cognitively and physically able to participate
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN SURVEY-COMPLETION: Parent/guardian is able to speak and read English or Spanish language
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN SURVEY-COMPLETION: Parent/guardian participant has signed informed consent for study participation
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN PRIM SESSION 5, "COMING TOGETHER": AYA agrees to participate in study
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN PRIM SESSION 5, "COMING TOGETHER": AYA randomized to PRISM intervention arm of study
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN PRIM SESSION 5, "COMING TOGETHER": AYA provides verbal assent or verbal consent if 18 or over for parent, caregiver, spouse, and/or significant other to be present during this session
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN PRIM SESSION 5, "COMING TOGETHER": Parent/caregiver/spouse/significant other is cognitively and physically able to participate
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN PRIM SESSION 5, "COMING TOGETHER": Parent/caregiver/spouse/significant other is able to speak and read in English or Spanish
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN PRIM SESSION 5, "COMING TOGETHER": Parent/caregiver/spouse/significant other participant has signed informed consent for study participation

Exclusion Criteria

• PATIENTS: Patient refusal to participate (any age), or parental refusal to participate for patients less than 18 years of age
• PATIENTS: Cognitively or physically unable to participate in interactive interview
• PATIENTS: Patient unable to speak in the English language
• PATIENTS: Patient unable to read in the English or Spanish language
• PATIENTS: Patient not receiving allogeneic HCT for treatment of malignancy
• HRV COMPONENT ONLY: Patient does not speak and read in English
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN PRIM SESSION 5, "COMING TOGETHER": AYA refusal to participate
• PARENTS, CAREGIVER, SPOUSES, OR SIGNIFICANT OTHERS TO PARTICIPATE IN PRIM SESSION 5, "COMING TOGETHER": Parent/guardian/caregiver/spouse/significant other participant is < 18 years of age