Low-Dose Aspirin in Decreasing Inflammation in Patients Undergoing Gynecologic Surgery

Inclusion Criteria

• Women undergoing gynecologic surgery for presumed benign indications that includes the removal of their fallopian tubes. This may include sterilization procedures, hysterectomy or partial or full adnexectomy
• Eligible women will have fulfilled their childbearing desires
• Age >= 21, considered low risk for prevalent fallopian tube cancer (not undergoing risk reducing surgery for a known BRCA mutation or other known hereditary pre-disposition syndrome, family history of ovarian cancer in a first degree relative)

Exclusion Criteria

• Women who have presumed or known gynecologic cancer
• Women less than 21 years of age
• Women who either in the last 12 weeks or are currently using regular (more than 1 dose per day for greater than 3 days of the week) aspirin therapy, non-steroidal anti-inflammatory drugs (NSAIDS), acetaminophen or chronic steroidal anti-inflammatory medications
• Women with known bleeding diathesis or bleeding disorder
• Women who do not consent for removal of both fallopian tubes
• Women with a history of gastritis or peptic ulcer disease requiring treatment. (Patients with a history of occasional H1 or H2 blocker use for gastro-esophageal reflux disease are NOT excluded)
• Women with reported aspirin or NSAID allergy
• Women with asthma and/or nasal polyps