This phase IV trial studies how well a basal-prandial-correctional insulin regimen works in managing high blood sugar in hospitalized cancer patients. Correct implementation of the basal-prandial-correctional insulin regimen facilitated by a dedicated treatment team may help to personalize the management of hyperglycemia in hospitalized cancer patients to achieve normal blood glucose levels and decrease hyperglycemia among Hispanic patients with a cancer diagnosis, addressing the disparity gap to improve outcomes.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT03904199.
PRIMARY OBJECTIVE:
I. To measure the proportion of euglycemia with the basal-prandial-correctional (BPC) protocol in hospitalized Hispanic patients and compare to historical data.
SECONDARY OBJECTIVE:
I. To compare the secondary endpoints in the hospitalized Hispanic patients treated with correct implementation of the BPC protocol to historical data.
OUTLINE:
Patients receive insulin glargine intravenously (IV) as basal insulin and then receive personalized correctional and prandial rapid-acting insulin IV doses to achieve a target blood glucose (BG) of 100-180 mg/dL.
Patients are followed up daily during hospitalization, up to the day of discharge.
Trial PhasePhase IV
Trial Typesupportive care
Lead OrganizationMoffitt Cancer Center
Principal InvestigatorSmitha Pabbathi