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Guadecitabine and Carboplatin in Treating Patients with Extensive Stage Small Cell Lung Cancer

Trial Status: administratively complete

This phase II trial studies how well guadecitabine and carboplatin work in treating patients with small cell lung cancer that has spread outside of the lung in which it began or to other parts of the body (extensive stage). Guadecitabine may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving guadecitabine and carboplatin may work better in treating patients with extensive stage small cell lung cancer compared to other standard of care chemotherapy drugs.