Structured Exercise Training for the Prevention of Decline in Physical Function among Prostate Cancer Patients, RESIST-ADT Trial

The trial implements an exercise regimen designed to improve muscle mass, muscle strength, and physical function among older men scheduled to undergo androgen deprivation therapy (ADT) for their prostate cancer, to prevent a decline in physical function. Men undergoing ADT for treatment of their prostate cancer experience a significant decline in muscle mass and muscle strength, which impacts their physical function, and a significant decrease in health-related quality of life and experience tiredness. This leads to frailty and a higher risk of falls. The information gained from this trial may help researchers learn how structured exercise training could prevent decline in physical function among older men with prostate cancer.

Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT04485767.

Trial PhaseNo phase specified

Trial Typesupportive care

Lead OrganizationDana-Farber Harvard Cancer Center

Principal InvestigatorShehzad Basaria

• Primary ID20-193
• Secondary IDsNCI-2020-06775
• ClinicalTrials.gov IDNCT04485767