Mindfulness Training and Oxytocin for the Reduction of Smoking and Craving among Smokers in Withdrawal

Inclusion Criteria

• Smoke at least 10 cigarette (cig)/day for the past year
• English fluency

Exclusion Criteria

• PILOT: Current Diagnostic and Statistical Manual of Mental Disorders (DSM-5) substance use disorder, excluding nicotine dependence (to minimize alcohol or drug withdrawal symptoms during the study sessions)
• PILOT: Current use of psychiatric medication for anxiety or mood disorders
• PILOT: Breath carbon monoxide (CO) levels < 8 ppm measured during study intake (to exclude individuals who overreport smoking in order to participate in the study)
• PILOT: Planning to quit or reduce smoking in the next 30 days
• PILOT: Current regular use of other nicotine-containing products
• PILOT: Current mindfulness or meditation practice of greater than 5 minutes per day
• MAIN STUDY: Current DSM-5 substance use disorder, excluding nicotine dependence (to minimize alcohol or drug withdrawal symptoms during the study sessions)
• MAIN STUDY: Any medical condition that would increase risk for study participation (such as sinus infection or other condition blocking access to the olfactory epithelium)
• MAIN STUDY: Women who are pregnant or nursing
• MAIN STUDY: Current use of psychiatric medication for anxiety or mood disorders
• MAIN STUDY: Breath carbon monoxide (CO) levels < 8 ppm measured during study intake (to exclude individuals who overreport smoking in order to participate in the study)
• MAIN STUDY: Planning to quit or reduce smoking in the next 30 days
• MAIN STUDY: Current regular use of other nicotine-containing products
• MAIN STUDY: Current mindfulness or meditation practice of greater than 5 minutes per day