This study explores the impact of radiation therapy on pelvic floor disorders in women treated for colorectal cancer. Women of all ages may experience changes in their pelvic floor function that may cause bothersome bladder or bowel symptoms or changes in sexual health. These symptoms become more common after menopause and with aging, but having a pelvic surgery or radiation therapy as a part of cancer treatment may also affect these symptoms. This study may help researchers improve their knowledge about women survivors of colorectal cancer.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT04623515.
PRIMARY OBJECTIVE:
I. To characterize the impact of radiation therapy on the lower urinary and bowel tract symptoms, (featuring urinary incontinence, irritative voiding symptoms, voiding dysfunction, bowel incontinence, and defecatory dysfunction) of female survivors of colorectal cancer 2-5 years after treatment.
SECONDARY OBJECTIVES:
I. To characterize sexual dysfunctions present in female colorectal cancer survivors 2-5 years after treatment and to determine the impact of radiation therapy compared to surgical treatment alone.
II. To examine the impact of radiation therapy on the sexual function of the partner of female survivors of colorectal cancer treated with radiation treatment.
OUTLINE:
Patients complete questionnaires over 30 minutes about bladder and bowel habits and sexual health. Patients' sexual partner also complete a survey over 5 minutes about sexual health and relationship satisfaction.
Trial PhaseNo phase specified
Trial TypeNot provided by clinicaltrials.gov
Lead OrganizationWake Forest University Health Sciences
Principal InvestigatorCandace Yvonne Parker-Autry
