This study collects samples of blood and/or urine to help develop new tests for the early detection and treatment of cancer and to improve the quality of life of women at increased risk of developing ovarian cancer and for those women diagnosed with the disease. It is difficult to detect early-stage ovarian cancer, and most women are diagnosed with advanced stage disease. Earlier detection of ovarian cancer leads to earlier treatment and improved survival and long term outcomes. Studying samples of blood and/or urine from patients with ovarian cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.
Additional locations may be listed on ClinicalTrials.gov for NCT00005095.
Locations matching your search criteria
United States
Illinois
Chicago
Northwestern UniversityStatus: Active
Contact: Lee P. Shulman
Phone: 312-472-4683
PRIMARY OBJECTIVES:
I. To identify and develop highly sensitive and specific tumor markers for the detection and management of ovarian cancer and other gynecological malignancies.
II. To use Cancer Differentiation Analysis (CDA) technology to identify screening tools for predicting ovarian cancer.
III. To identify new prevention approaches and therapies.
IV. To identify measures to improve the quality of life for women at increased risk for developing ovarian cancer and for women diagnosed with ovarian cancer.
OUTLINE:
HIGH-RISK POPULATION: Patients undergo collection of blood and urine samples 1-4 times per year. Patients who undergo surgery per standard of care, also undergo collection of ovarian tissue at time of surgery. Patients also complete questionnaires about how they feel, their medical history, or their family’s medical history, and may participate in an interview over 15-30 minutes. Patients also receive a consultation with a genetic counselor.
GYNECOLOGIC OR GYNECOLOGIC ONCOLOGY AND TISSUE POPULATION: Patients undergo collection of blood and urine samples at study visits, and undergo collection of tissue, ascites, and pleural fluid during standard of care procedures. Patients also complete questionnaires about how they feel, their medical history, or their family’s medical history, and may participate in an interview over 15-30 minutes.
CONTROL POPULATION: Participants undergo collection of blood samples at study visits. Patients also complete questionnaires over 10 minutes about their health history, and may participate in an interview over 15-30 minutes.
Trial PhaseNo phase specified
Trial TypeNot provided by clinicaltrials.gov
Lead OrganizationNorthwestern University
Principal InvestigatorLee P. Shulman