This clinical trial studies the effects of Tai Chi Easy on immune function and quality of life in patients with multiple myeloma who are undergoing stem cell transplantation. Stem cell transplantation is associated with a high symptom burden and impaired quality of life during the procedure. Tai Chi Easy (TCE) is a validated and tested version of meditative movement. TCE is a standardized protocol used in several prior studies that has been manualized and has a formal training program for instructors. The protocol is taught as a series of repeated and simple-to-learn movements. The TCE program may help improve patient’s quality of life and symptoms, improve immune function, and potentially improve the anti- multiple myeloma tumor response.
Additional locations may be listed on ClinicalTrials.gov for NCT04760405.
See trial information on ClinicalTrials.gov for a list of participating sites.
PRIMARY OBJECTIVES:
I. To examine practicality and implementation of immunoassays during autologous stem cell transplantation (ASCT). (i.e. peripheral blood natural killer [NK]-cell phenotype, NK cell activity, serum immunoglobulins, lymphocyte subsets).
II. Investigate the impact of TCE on health related quality of life (HRQOL) including anxiety, depression, pain, and multiple myeloma symptom burden.
OUTLINE:
Within 7 days prior to transplant, patients participate in two TCE small group training sessions via Zoom with a certified instructor over 30 minutes - 1 hour. After training completion, patients receive an MP4 file download of the practice, online links, and a written manual on the TCE movements and perform a minimum of 10 minutes a day of TCE for up to 100 days post-transplant at home. Additionally, patients undergo blood sample collection on study.
Trial PhaseNo phase specified
Trial Typesupportive care
Lead OrganizationBanner University Medical Center - Tucson
Principal InvestigatorKrisstina Lorraine Gowin
