Watercress for the Detoxification of Environmental Toxicants and Carcinogens

Inclusion Criteria

• Male or female age 18 years or older. Participants can be smokers or non-smokers * Smokers must report daily use (at least one cigarette per day)
• In good physical health with no unstable or serious medical conditions as determined by the licensed medical professional
• In stable and good mental health (i.e. not currently, within the past 6 months, experiencing unstable or untreated psychiatric diagnosis, including substance abuse) as determined by the licensed medical professional
• Not using any medications that may affect the Nrf2 pathway
• Women who are not pregnant or nursing or planning to become pregnant
• Participants have provided written informed consent to participate in the study

Exclusion Criteria

• Significant immune system disorders, respiratory diseases, kidney or liver diseases or any other medical disorders that may affect biomarker data as determined by the licensed medical professional
• History of type I or II diabetes
• Vital signs outside of the following range (participants failing for vital signs will be allowed to re-screen once): * Systolic blood pressure (BP) < 90 or >= 160 mmHg * Diastolic BP < 50 or >= 100 mmHg * Heart rate < 45 or >= 105 bpm
• Not willing to abstain from eating cruciferous vegetables during the course of the study
• Known allergy or contraindication to watercress or any of the study product components
• Phenylketonuria (PKU) disease (as some of the flavoring packets may contain phenylalanine)
• Plans to quit smoking in the next three months