This clinical trial studies how well multi-modal acceptance and commitment therapy (M-ACT) works to reduce anxiety, depression, and fear in patients with advanced cancer. Behavioral therapy such as M-ACT, use techniques to help patients change the way they react to environmental triggers that may cause a negative reaction. Studying M-ACT therapy outcomes may help doctors better understand the causes for anxiety, fear, depression, and advance care planning.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT04773639.
PRIMARY OBJECTIVES:
I. To evaluate the effects of multi-modal acceptance and commitment therapy (M-ACT) on Advance Care Planning (ACP)(primary outcome) and targeted psychosocial outcomes of anxiety and depression (anx/dep) symptoms, fear of dying, and sense of life meaning (secondary outcomes).
II. To assess the association between anx/dep symptoms and ACP.
EXPLORATORY OBJECTIVE:
I. To evaluate M-ACT’s hypothesized mechanisms, reflecting the National Institute of Nursing Research’s (NINR) priority on identifying intervention mechanisms.
OUTLINE: Patients are randomized to 1 of 2 arms.
ARM I: Patients receive M-ACT, consisting of group therapy for 2 hours (in-person) or 30-45 minutes (online), and daily online check-ins for 5 minutes for up to 5 weeks.
ARM II: Patients receive usual care for 5 weeks.
After completion of the study intervention, patients are followed for 2 months.
Trial PhaseNo phase specified
Trial Typesupportive care
Lead OrganizationUniversity of Colorado – Boulder
Principal InvestigatorJoanna Arch
