A Study of Sitravatinib Alone or in Combination with Other Anticancer Therapies in
Advanced or Metastatic Malignancies
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT04887870.
Sitravatinib is a spectrum-selective receptor tyrosine kinase (RTK) inhibitor that
inhibits several closely related RTKs including the TAM family (Tyro3/Axl/MERTK), VEGFR2,
KIT, and MET.
The current study is designed to allow continued access to sitravatinib and to evaluate
the safety and tolerability of sitravatinib alone or in combination with other anticancer
therapies in patients who are deriving clinical benefit in a previous parent clinical
trial.
Lead OrganizationMirati Therapeutics