Two Types of Surgery (Minimally Invasive Proximal Gastrectomy versus Total Gastrectomy) for the Treatment of Non-metastatic, Proximal Gastric Cancer and Gastroesophageal Junction Cancer
This clinical trial compares two types of surgery, minimally invasive proximal gastrectomy versus total gastrectomy, in treating patients with gastroesophageal junction cancer or stomach (gastric) cancer that has not spread to other parts of the body (non-metastatic) and is located in the upper part of the stomach (proximal). Total gastrectomy is surgery to remove the entire stomach, and is the current standard treatment for non-metastatic gastric cancer or gastroesophageal junction cancer. After total gastrectomy, patients often experience impaired appetite, weight loss, anemia, and decreased quality of life. Minimally invasive proximal gastrectomy is a less invasive type of surgery and only removes the upper part of the stomach, which may lead to fewer side effects and improved recovery. Minimally invasive proximal gastrectomy may improve post-surgical outcomes, including increased appetite and quality of life, when compared to total gastrectomy.