A New Imaging Method to Identify Radiation-Induced Uterine Injury in Women That Have Had Pelvic Radiation Therapy
This clinical trial tests how well a new imaging method, shear-wave-elastography (SWE) ultrasound and magnetic resonance imaging (MRI), can identify radiation-induced uterine injury (RIUI) in women that have had pelvic radiation therapy (PRT). Ultrasound imaging is a noninvasive medical test. A small probe and some gel are used. Sound waves then travel from the probe through the gel and into the body to create an image. SWE ultrasound is a specific type of ultrasound that is used to measure tissue strength. MRI is a non-invasive test doctors use to image the body. MRI uses a powerful magnetic field, radio waves and a computer to produce detailed images of the inside of the body. RIUI can affect fertility and pregnancy outcomes, leading to diminished quality of life for female cancer survivors and their children. Identifying more effective strategies to identify RIUI in female cancer survivors is needed. Using SWE and MRI may be helpful in identifying RIUI in women that have had PRT.