This clinical trial develops an intervention (acceptance and commitment therapy) for avoidance-related opioid (medications prescribed for pain relief) misuse in patients with cancer under palliative care (pain and symptom management) of a provider. Acceptance and commitment therapy is a psychological intervention that uses acceptance, mindfulness, commitment, and behavior change strategies to increase psychological flexibility. Researchers hope this study will provide more information about psychological interventions for patients with cancer receiving palliative care.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT05643027.
Locations matching your search criteria
United States
Massachusetts
Boston
Dana-Farber Cancer InstituteStatus: Active
Contact: Miryam Yusufov
Phone: 617-582-7618
PRIMARY OBJECTIVES:
I. Adapt and refine a six-session behavioral intervention for at-risk individuals prescribed opioids for cancer-related pain at an outpatient palliative care clinic, based on the current treatment development phase (Dana-Farber Cancer Institute [DFCI] Institutional Review Board [IRB] Protocol # 19-035).
II. Assess the feasibility and acceptability of the intervention by conducting a randomized pilot trial of the revised intervention (“ACTION”) for cancer patients on opioid therapy, and at risk for substance use disorder.
OUTLINE: Patients are randomized to 1 of 2 groups.
ACT GROUP: Patients undergo acceptance and commitment therapy (ACT) intervention by phone, virtually via Zoom, or in-person over 30 minutes for 6 sessions.
WAITLIST GROUP: Six weeks after study enrollment, patients are offered the ACT intervention by phone, virtually via Zoom, or in person over 30 minutes for 6 sessions.
Trial PhaseNo phase specified
Trial Typesupportive care
Lead OrganizationDana-Farber Harvard Cancer Center
Principal InvestigatorMiryam Yusufov
