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Comparison of the Performance of Monopolar Current Cutting Knife and Bipolar RFA Knife in Endoscopic Submucosal Dissection for Gastrointestinal Neoplastic Lesions

Trial Status: closed to accrual

This clinical trial compares the effect of using the monopolar current cutting knife and the bipolar radiofrequency ablation (RFA) knife for patients undergoing endoscopic submucosal dissection for gastrointestinal neoplastic lesions, including polyps. Endoscopic submucosal dissection (ESD) is a minimally invasive procedure that allows the removal of lesions without the need to resort to major surgery. Traditionally, the preferred tools for removing this tissue are electrocautery knives that cut out the tissue and reduce bleeding by applying heat to the tissue. One type of knife is the monopolar knife which uses electrical energy coming from the knife to the lesion and returning to the knife to reduce bleeding by applying heat to the tissue. The bipolar RFA knife uses electrical energy that passes between two points on the knife to cut the lesions. Using the bipolar RFA knife may reduce the surgical time and lead to less side effects than the monopolar knife in patients undergoing ESD for gastrointestinal neoplastic lesions.