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Second Window Imaging using Indocyanine Green (TumorGlow-CNS) to Identify Tumor Tissue During Surgery for Nervous System Tumors

Trial Status: active

This phase I/II trial tests how well second window imaging using indocyanine green (ICG) (TumorGlow [trademark] central nervous system [CNS]) identifies tumor tissue from normal tissue in patients during surgery for brain or spine (nervous system) tumors. In addition to primary brain tumors, many other types of cancers spread to the brain and may require surgery to remove. Near infrared (NIR) imaging uses wavelengths in the infrared range to directly visualize tissue. ICG is a dye that causes tumor tissue to glow when used with the NIR imaging system. Using ICG with NIR imaging during surgery may improve identification of tumor tissue from normal tissue resulting in improved resection of the tumor in patients with nervous system tumors.