This clinical trial evaluates an exercise and health behavior program (modeled after cardiac rehabilitation) in people with a history of breast cancer to find out whether it improves heart health after cancer treatment. Breast cancer survivors have 1.8 times the risk of cardiovascular mortality compared to women without breast cancer. This elevated risk is due to shared risk factors (e.g., obesity, tobacco use), side effects of some cancer treatments (e.g., cardiotoxic chemotherapy, hormone-related treatments, and radiation), and health behaviors (e.g., sedentary lifestyle, diet). This study may help researchers determine the impact of an exercise and health behavior program on heart disease risk in patients with breast cancer.
Additional locations may be listed on ClinicalTrials.gov for NCT06055803.
Locations matching your search criteria
United States
California
San Francisco
University of California San FranciscoStatus: Active
Contact: Alexis Beatty
Phone: 415-502-6191
Zuckerberg San Francisco General HospitalStatus: Active
Contact: Alexis Beatty
Phone: 415-502-6191
PRIMARY OBJECTIVE:
I. To pilot test a multi-disciplinary health behavior intervention in people with a history of breast cancer to reduce heart disease risk after cancer treatment.
SECONDARY OBJECTIVE:
I. Establishing preliminary data on changes in objective and patient-reported measures including 6MWD, quality of life, health behaviors (medication adherence, physical activity, healthy eating), cognitive function, and potential mechanisms of action of the intervention including self-efficacy, social isolation, and optimism.
OUTLINE:
Patients participate in an exercise and health behavior program consisting of weekly alternating individual sessions over 30-60 minutes and group sessions over 1-2 hours composed of individualized plans and education for exercise, nutrition, emotional well being, survivorship, cardiovascular risk factors, and other topics that may include tobacco cessation, specialized rehabilitation services, body image, sex and intimacy and financial barriers for 12 weeks. Patients wear a Fitbit, undergo body measurements and six minute walk-tests throughout the trial.
Upon completion of the study intervention, patients attend a graduation ceremony and are followed up at 6 months, and 12 months.
Trial PhaseNo phase specified
Trial Typesupportive care
Lead OrganizationUniversity of California San Francisco
Principal InvestigatorAlexis Beatty
