A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer

Inclusion Criteria

• Male or female, aged ≥18 years when signing the ICF.
• Histologically diagnosed with SCLC.
• Diagnosed with LS-SCLC (stage Ⅰ-Ⅲ of the AJCC 8th edition of the cancer staging), which can be safely treated with curative radiation doses.
• Major organs are functioning well.

Exclusion Criteria

• Histologically or cytologically confirmed mixed SCLC.
• Subjects suitable for surgery. Subjects who are suitable for surgery but refuse surgical treatment can be included.
• Patients who have previously received systematic anti-tumor treatments for small cell lung cancer, including but not limited to radiotherapy, chemotherapy, and immunotherapy.
• Patients with other active malignancies within 5 years or at the same time.
• Subjects with known history of severe allergy to any monoclonal antibody.
• Subjects with known anaphylaxis to carboplatin/cisplatin or etoposide.
• In the judgment of the investigator, subjects who have any other factors that may lead to a premature discontinuation.