Minimally-Invasive Stabilization of Pelvic Metastases with Photodynamic Nails for the Improvement of Functional Outcomes and Pain Control in Patients with Metastatic Cancer
This phase I trial tests the safety and effectiveness of photodynamic nails for the minimally-invasive stabilization of cancer that has spread from where it first started (primary site) to the pelvis (metastatic) for the improvement of functional outcomes and pain control. The pelvis is frequently involved by metastatic bone disease. Traditionally, when the hip joint is affected, a major operation such as total hip replacement is needed to restore stability, relieve pain, and allow walking. A minimally invasive procedure may be appropriate for many patients. One strategy is to use an Illuminoss device, which is a polymer-filled balloon that can occupy a bone defect and give the bone more strength. The Illuminoss device has been cleared by the Food and Drug Administration for use in bone fractures, but is still being studied in metastatic bone disease. Information gained from this study may allow researchers to determine whether there are benefits in pain control, function, and walking with the use of photodynamic nails.