Evaluation of Ultrasound Vibroelastography in Post-Prostatectomy Erectile Dysfunction in Patients with Localized Prostate Cancer
This clinical trial tests the performance of ultrasound vibroelastography (penile ultrasound) in post-prostatectomy erectile dysfunction in patients with localized prostate cancer. Erectile dysfunction or “ED” is a common side effect after surgical treatment for men with prostate cancer. This is sometimes caused by issues with nerves to the penis, but also by abnormal blood flow and scar tissue within the penis. Currently, questionnaires and sometimes ultrasound studies (imaging studies using soundwaves) are used to evaluate the changes in blood flow and scar tissue. Unfortunately, these tests have significant flaws, which limit how useful they are. Penile ultrasound involves using sound waves to create pictures of tissues and take measurements of blood flow. Vibroelastograpy involves creating a gentle vibration, and measuring changes in the tissue. It can be used at the same time as standard ultrasound. Changes in these measurements are often seen when there is “fibrosis” or scar tissue, which can be a sign of more significant erectile dysfunction. This study is being done to determine if this technology can help to predict which men are more likely to recover their erectile function, and what types of treatments may be best used in those circumstances.