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External Beam Radiation Therapy for Preoperative Treatment of Patients with Soft Tissue Sarcoma

Trial Status: active

This phase II trial studies how well a shortened course of external beam radiation therapy before surgery works in treating patients with soft tissue sarcoma of the extremities, trunk or retroperitoneum. External beam radiation therapy uses high energy protons to kill cancer cells and shrink tumors. Radiation therapy given before surgery is a standard treatment option for patients with soft tissue sarcomas and is typically delivered in 25 treatments over 5 weeks. However, many sarcoma patients often have to travel great distances for treatment, and even for patients who live nearby, daily treatment for 5 weeks can be a considerable burden. Researchers want to test how well a shortened course of radiation therapy before surgery works in treating patients with soft tissue sarcomas.