Comparing the Impact of Prostate Capsule-Sparing Cystectomy Compared to Nerve-Sparing Radical Cystectomy on Functional Outcomes in Patients with Bladder Cancer
This clinical trial compares the effect of prostate capsule-sparing cystectomy to nerve-sparing radical cystectomy on functional outcomes in patients with bladder cancer. Prostate capsule-sparing cystectomy is surgery to remove the bladder and only the inner part of the prostate. The prostate is a gland surrounded by a capsule. In the prostate capsule-sparing cystectomy, the inside tissue of the prostate gland is removed while leaving the capsule intact. This method is also called “simple prostatectomy.” By leaving the capsule intact, the nerves next to the seminal vesicles are preserved. This surgical method helps to limit damage to the surrounding nerves, which helps decrease the risk of erectile dysfunction and urinary incontinence. Nerve-sparing radical cystectomy is surgery to remove the entire bladder and prostate but save the nerves that run along the sides of the outer shell of the prostate. Sparing these nerves helps to decrease erectile dysfunction in patients who are interested in maintaining sexual activity after surgery, and improve urinary continence. A prostate capsule-sparing cystectomy may be more effective compared to a nerve-sparing radical cystectomy at preserving functional outcomes without compromising cure in patients with bladder cancer.