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Contrast-Enhanced Imaging for Diagnosing Bladder Cancer Stage in Patients Undergoing Bladder Surgery

Trial Status: active

This clinical trial is evaluating whether a single magnetic resonance imaging scan with contrast agents gadobutrol and ferumoxytol can accurately diagnose the stage of bladder cancer in patients who are scheduled to have a resection (transurethral resection of the bladder tumor [TURBT]) or a complete removal of the bladder (cystectomy). Magnetic resonance imaging is a procedure in which radio waves and a powerful magnet linked to a computer are used to create detailed pictures of areas inside the body. These pictures can show the difference between normal and diseased tissue. Gadobutrol and ferumoxytol are contrast agents that are injected into the body and taken up by certain tissues, making the tissues easier to see in imaging scans. Giving gadobutrol and ferumoxytol before magnetic resonance imaging may work better at diagnosing the stage of bladder cancer in patients who are scheduled to have TURBT or a cystectomy.