This clinical trial tests how well a crowdsourced, community engaged educational intervention improves the uptake of human papillomavirus (HPV) vaccination and self collected screening among mother-daughter dyads in Nigeria. Expanding HPV vaccination for girls and HPV self-collection for women can reduce the global burden of cervical cancer. However, HPV vaccination and self-collection services are rarely implemented simultaneously among mother-daughter dyads, leaving a critical gap in cervical cancer prevention. A combined mother-daughter intervention, tailored and adapted to local contexts, with education on cervical cancer and access to onsite services may increase vaccination and screening among mother-daughter dyads in Nigeria.
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PRIMARY OBJECTIVE: 
I. To explore the impact of this crowdsourced, community-engaged mother-daughter campaign and implementation strategy bundle on HPV vaccination among girls and HPV screening among their mothers in Nigeria over 6 months in 18 Nigerian local government areas.
OUTLINE: Local government areas are randomized to start at month 0, 2, 4 or 6.
Mother-daughter pairs receive a text message reminder and attend the Mother-Daughter Day event where they receive education on cervical cancer control from trained community health workers. Daughters receive access to HPV vaccinations immediately on site in a private space. Mothers receive access to self collected HPV screening immediately on site in a private space.
After completion of the study intervention, participants are followed up at 3, 6 and 12 months.
Trial PhaseNo phase specified
Trial Typeprevention
Lead OrganizationSiteman Cancer Center at Washington University
Principal InvestigatorJuliet Iwelunmor