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New PET Scan (68Ga-FAPI-46) for People with Cancers

Trial Status: active

This exploratory trial is evaluating a new imaging tracer (68Ga-FAPi-46) with positron emission tomography (PET)/computed tomography (CT) to determine where and to which degree the tracer (68Ga-FAPi-46) accumulates in normal and cancer tissues (the biodistribution) in patients with solid tumors or hematologic (blood) cancers. 68Ga-FAPI-46 is a tracer used in PET scans. It attaches to a protein (called FAP) found on certain support cells in the body, called fibroblasts. Around many tumors, these fibroblasts become very active — we call them cancer-associated fibroblasts. Because of this, 68Ga-FAPI-46 PET scans can light up areas where cancer is located.

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